Universität Wien

270305 VO Nucleoside and Nucleic Acid Chemistry (2025W)

4.00 ECTS (2.00 SWS), SPL 27 - Chemie
Moodle

An/Abmeldung

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Details

max. 15 Teilnehmer*innen
Sprache: Englisch

Prüfungstermine

Lehrende

Termine (iCal) - nächster Termin ist mit N markiert

The course will take place on-site in the Seminar Room 3 in the Chemistry building, every Thursday 14:45 to 16:15. The first lecture will be on Thursday 16.10.

  • Donnerstag 09.10. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 16.10. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 23.10. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 30.10. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 06.11. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 13.11. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 20.11. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 27.11. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 04.12. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 11.12. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 18.12. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 08.01. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 15.01. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 22.01. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
  • Donnerstag 29.01. 14:45 - 16:15 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1

Information

Ziele, Inhalte und Methode der Lehrveranstaltung

The lecture will focus on the structural and synthetic aspects of the chemistry of nucleic acids and of the building blocks of life, nucleosides and nucleotides. We will study the different molecular components of nucleosides: sugar, nucleobases, phosphodiesters all the way up to the structure of nucleic acids, in their single-stranded and double-stranded forms. This will allow us to understand how chemists came up with synthetic methods to produce nucleosides and nucleic acids and how they brought about chemical modifications too. We will discuss in which therapeutical context chemical modifications to nucleosides and nucleic acids are relevant, where they can be introduced and what their effects are. We will briefly talk about the biosynthesis of nucleosides and nucleic acids. Finally, a large portion of the lecture will be dedicated to modern methods for DNA and RNA synthesis.This is the more chemistry-oriented counterpart of the lecture "Nucleic Acid Biotechnology", available in the Summer Semester.

Art der Leistungskontrolle und erlaubte Hilfsmittel

Final Examination at the end of the semester (in English)

Mindestanforderungen und Beurteilungsmaßstab

Understanding the concepts related to structure, function, properties and synthesis of natural and non-natural nucleoside/nucleotides/nucleic acids. Focus is on the chemistry aspect of these molecules, how they are defined and how they are made.

Understanding in which context they can (and have) become crucial therapeutic tools.

Prüfungsstoff

Chemical structures and nomenclature
Conformational analysis
Nucleoside synthesis
Nucleic acid structure and function

Literatur

Nucleic Acids in Chemistry and Biology, Michael Gait, RSC Publishing

Zuordnung im Vorlesungsverzeichnis

CH-CBS-07, BC-CHE II-3, CH-FE, BC-Wahl, Freie Wahlfächer und Transferable Skills, UF MA CH 02c

Letzte Änderung: Fr 13.03.2026 14:07