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300369 UE Genomic approaches to variation and adaptation (2017S)

5.00 ECTS (3.00 SWS), SPL 30 - Biologie
Continuous assessment of course work


Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).


max. 12 participants
Language: English


Classes (iCal) - next class is marked with N

Thursday 02.03. 14:00 - 14:30 Übungsraum 1 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Monday 29.05. 09:00 - 17:00 Übungsraum 1 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Tuesday 30.05. 09:00 - 17:00 Übungsraum 1 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Wednesday 31.05. 09:00 - 17:00 Übungsraum 1 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Thursday 01.06. 09:00 - 17:00 Übungsraum 1 (Fakultätszentrum für Biodiversität) Rennweg 1.OG
Friday 02.06. 09:00 - 17:00 Übungsraum 1 (Fakultätszentrum für Biodiversität) Rennweg 1.OG


Aims, contents and method of the course

Population genomics and genome evolution from next-generation sequencing data, such as whole-genome sequencing, RAD sequencing and transcriptomics. We will exemplify genomic investigation procedures to trace natural selection, genetic ancestry, function, structure and gene-environment interactions, starting with introducing basic omic approaches, such as de novo assembly and mapping.

Assessment and permitted materials

Active participation in the practical 4 points, two short written exams 5 points each; mini presentation 6 points; thus totalling 20 points.
Credit key: <10 points: 5; 11-12 points: 4; 13-14 points: 3; 15-17 points 2; 18-20 points: 1.

Minimum requirements and assessment criteria

The students are able to understand and apply basic pipelines in genomics (e.g., quality check and filtering of NGS reads; mapping; vcf manipulation; differential expression; SNP calling), and they have good knowledge and skills in the fields of evolutionary and ecological research. Attendance of the complementary lecture VO300127 is highly recommended.

Examination topics

Practical work at the computer; demonstration
Integration of methods and data in a scientific protocol; presentation of a specific aspect pertaining to the content of this course

Reading list

Association in the course directory

MBO 5, MEV W-1, MEV W-5, MEV W-6, 30.06, MES5

Last modified: Mo 07.09.2020 15:43