301101 VO Epigenetics- From basic mechanisms to medical applications (2020W)
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Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
Details
Language: English
Examination dates
Lecturers
Classes
Block, täglich 04 .11. bis 26. 11.2019 von 17:00 bis 18:30 Uhr
Grosser Hörsaal/Histologie am Zentrum für Anatomie und Zellbiologie Schwarzspanierstraße 17, 1090 Wien
Information
Aims, contents and method of the course
Assessment and permitted materials
Written exam.
Minimum requirements and assessment criteria
A minimum of 55% of the achievable points is necessary for a positive grade.
sehr gut 90-100%
gut 80-89%
befriedigend 70-79%
genügend 55-69%
nicht genügend 0-54%
sehr gut 90-100%
gut 80-89%
befriedigend 70-79%
genügend 55-69%
nicht genügend 0-54%
Examination topics
Contents of the course units, PDF of power point presentations on Moodle.
Reading list
Provided on Moodle.
Association in the course directory
MGE III-1, MMB IV-2, MMB IV-3, MMB W-2, PhD-MB 3, MMEI III, UF MA BU 01, UF MA BU 04,
Last modified: Tu 08.06.2021 13:09
Part Seiser:
1. Introduction
History of Epigenetics
Chromatin composition
2. Basic epigenetic mechanisms
DNA methylation
Histone modification/remodeling
Non-coding RNA
3. Epigenetic Phenomena
Imprinting
X-chromosome inactivation
Position effect variegation/Drosophila Epigenetics
(Wolfgang Miller)
4. Techniques to study the epigenomePart Egger:
1. Epigenetic signatures in development and differentiation
Reprogramming of the epigenome during germ cell formation and after fertilization
The concept of cellular memory (Polycomb- Trithorax)
2. Artificial epigenetic reprogramming
Cloning, induced pluripotent stem cells
3. Influence of the Environment / Epigenetic alterations in disease
Tumor epigenetics
Imprinting defects
Complex disease
Mouse models to study epigenetics
4. Epigenetic therapy
5. Development of epigenetic biomarkers