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301102 UE Practical Course in Molecular Genetics and Pathology (2021S)

Epigenetics

10.00 ECTS (6.00 SWS), SPL 30 - Biologie
Continuous assessment of course work
ON-SITE

Registration/Deregistration

Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).

Details

max. 12 participants
Language: German

Lecturers

Classes

Course requirements and admission criteria:
1. Attendance at the preliminary meeting (‘Vorbesprechung’);
2. Successfully completion of the lecture VO301101 ‘Epigenetics’ (WS) Egger, Seiser;
3. Master’s students in A 066 877 'Genetics und Developmental Biology' will have preferential access;
4. Additional requirements for students who have not completed their bachelor's degree in the bachelor's program Biologie at the University of Vienna in the areas of BMG or BMB: External students who got practical courses (UE) as requirement by the admission to the Master´s program have to complete them in advance (bring a copy of your admission letter and a current transcript to the preliminary meeting).


Information

Aims, contents and method of the course

1. Telomeric trans-silencing and PEV in the Drosophila germ line

2. In vivo DNA/histone modification assays in Drosophila polytene chromosomes

3. Monitoring DNA methylation dynamics in human tissue samples via COBRA analyses

4. Effect of linc RNAs on reprogramming chromatin and promoting human cancer metastasis

5. The effect of HDAC inhibitors on histone marks and expression in somatic mammalian cells

Assessment and permitted materials

Compulsory attendance; the evaluation consists of different performances: active participation and results obtained, written report, theoretical knowledge including final exam (the percentage of the subgrades will be announced by the course leader); each of the subgrades must have a positive evaluation.

Minimum requirements and assessment criteria

Students need to perform the experiments, write a protocol and give a final presentation

Examination topics

scripts and literature provided by teachers

Reading list

C. David Allis, Marie-Laure Caparros, Thomas Jenuwein, Danny Reinberg: Epigenetics 2nd edition

Association in the course directory

MGE I-2, Biologische Chemie: BIO II-1

Last modified: We 26.05.2021 07:49