Universität Wien

322077 VU Overcoming the Skin Barrier: Drug Delivery via the Dermal Route - M7 (2023W)

1.00 ECTS (1.00 SWS), SPL 32 - Pharmazie
Continuous assessment of course work

Registration/Deregistration

Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).

Details

Language: German

Lecturers

Classes

Lectures are held in class every Tuesday, 9:45-11:15, Seminarraum 2E 411.

Di, 03.10.2023
Di, 10.10.2023
Di, 17.10.2023
Di, 24.10.2023
Di, 07.11.2023
Di, 14.11.2023
Di, 21.11.2023


Information

Aims, contents and method of the course

The aim of this course is to obtain an overview about the development of dermal formulations and the techniques required for their production and characterisation. Contents include skin biology, colloidal formulations in the nanometer range, high and low energy production techniques as well as established methods for characterisation of dermal formulations and skin itself (formulation analysis: optical light microscopy and electron microscopy, light scattering techniques, rheology; skin analysis: TEWL, hydration, pH, sebum; penetration/permeation analysis: diffusion cells, tape stripping, ATR-FTIR spectroscopy, confocal Raman spectroscopy).

Methods: The contents are presented and discussed by means of ppt presentations.

Assessment and permitted materials

Short written examinations are handed out every two sessions.

Minimum requirements and assessment criteria

All exams have to be evaluated in a positive manner (>60%). The grading depends on the achieved points:
exam 1 = 1 point
exam 2 = 2 points
exam 3 = 2 points
5 points = Sehr Gut, 4 points = Gut, 3 points = Befriedigend, 4 points = Genügend, 5 points = Nicht Genügend

Examination topics

Contents of the presentations.

Reading list

Literatur zum Thema Haut und Penetration von Arzneistoffen:
- Percutaneous Penetration Enhancers, Eds. Dragicevic & Maibach, Springer (2015)
- Transdermal Drug Delivery, Eds. Guy & Hadgraft, Marcel Dekker Inc, 2nd edition (2002)
- Mechanisms of Transdermal Drug Delivery, Ed. Potts, CRC Press, 1st edition (1997)

Literatur zum Thema kolloidale Arzneiformen:
- Bauer/Frömming/Führer: Pharmazeutische Technologie (Eds. Lippold/Müller-Goymann/Schubert, Wiss. Verlagsges. Stuttgart, 10. Auflage, 2017)
- Innovative Arzneiformen (Eds. Mäder & Weidenauer, Wiss. Verlagsges. Stuttgart, 2009)
- Voigt: Pharmazeutische Technologie für Studium und Beruf (Ed. Fahr, Wiss. Verlagsges. Stuttgart, 12. Auflage, 2015)

Literatur zu den besprochenen Methoden:
- Grundlagen der Licht- und Elektronenmikroskopie, Ed. Linnemann & Kühl, UTB GmbH, 2017.
- Laser Light Scattering, Eds. Johnson & Gabriel, Dover Classics, Dover Publications Inc., 1995.
- Zetapotential und Partikelladung in der Laborpraxis, Ed. Müller, Wiss. Verlagsges. Stuttgart, 1996.
- Spektroskopische Methoden in der organischen Chemie, Eds. Hesse, Meier, Zeeh, Thieme, 2005.
- Confocal Raman Microscopy, Eds. Dieing, Hollricher, Toporski, Springer-Verlag Berlin Heidelberg, 2011.
- Das Rheologie-Handbuch, Ed. Mezger, Vincentz Network, 2016.

Association in the course directory

MA8, MA23

Last modified: We 13.09.2023 08:48