320093 VO Applied Pharmacogenetics (2011W)

This course is intended to provide insights into the methodology of pharmacogenetics.
The pharmacokinetics of many drugs is affected by activity of specific cytochrom-P450-enzymes. Genotyping of test subjects (the course participants) will be performed by analysing genomic DNA. The polymorphism of cytochrom-P450 2D6 concerning a particular mutation will be determined. The therapeutic relevance of Cytochrome P450 polymorphism will be discussed.