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270052 SE Chemische Biologie (2021W)

3.00 ECTS (2.00 SWS), SPL 27 - Chemie
Prüfungsimmanente Lehrveranstaltung
DIGITAL

An/Abmeldung

Hinweis: Ihr Anmeldezeitpunkt innerhalb der Frist hat keine Auswirkungen auf die Platzvergabe (kein "first come, first served").

Details

max. 25 Teilnehmer*innen
Sprache: Englisch

Lehrende

Termine

The dates and times of this seminar are the following:
10 am - 12.30 pm
10.11, 11.11., 12.11., 17.11., 18.11., 19.11.
22.11., 24.11., 25.11., 29.11., 30.11., 01.12.
Seminar will be held online via Zoom link.


Information

Ziele, Inhalte und Methode der Lehrveranstaltung

TEACHING METHODS
- formal lectures with PowerPoint slides
- exercises to re-cap previous lecture
- group discussion and exercises on journal articles
- data analysis exercises
- class discussion activities (mind-mapping, peer-teaching etc.)
- "homework"; reading journal articles (about 4-5 over the course)

LEARNING OUTCOMES
At the end of the course, students should:
- be familiar with the topics encompassed by the field of Chemical Biology
- be aware of recent developments in the field
- understand some of the challenges and controversies in the field
- be able to read, understand and critically evaluate a journal article
- be able to discuss a journal article or data set and draw conclusions from it
- be able to apply the knowledge and skills learnt to their master theses and in other situations

TOPICS
1. Introduction to Chemical Biology (MM)
2. Peptides as Molecular Probes (MM)
3. Peptides as Therapeutics (MM) _ Assessment exercise
4. Protein Structures and Functions (MM)
5. Techniques in Chemical Biology (MM)
6. Chemical Biology in Action (MM) _Assessment exercise
7. Basic pharmacology and molecular targeted therapies (CB)
8. Protein kinases as anticancer drug targets (CB)
9. G protein-coupled receptors as drug targets (CB)_Assessment exercise
10. Binding proteins: from therapeutic antibodies to affibodies and antibody mimetics (CB)
11. Anticancer vaccines (CB)
12. Antibiotics and discovery of new drugs (CB)_Assessment exercise

Art der Leistungskontrolle und erlaubte Hilfsmittel

Participation, assessment exercises, final exam.

Mindestanforderungen und Beurteilungsmaßstab

ASSESSMENT
- attendance of at least 9 lectures is required (if you miss more than 3 lectures you will obtain a 5 since this is a continuous assessment course / prüfungsimmanente LV).
- 5% of the course grade will be based on participation during the course.
- 55% of the course grade will be based on exercises given during the course period (4 exercises will be given).
- 40% of the course grade will be based on a final assessment to be done in students’ own time and submitted after the course ends by January 2022.
- grades will be given as: 0–49% (5), 50–59% (4), 60–74% (3), 75–89% (2), 90–100% (1)

Prüfungsstoff

Literatur


Zuordnung im Vorlesungsverzeichnis

BC-3, BIO II-3, CHE II-3, UF MA CH 02c

Letzte Änderung: Fr 12.11.2021 09:09