270201 PR Data Science in Bioanalysis (2023S)
Prüfungsimmanente Lehrveranstaltung
Labels
An/Abmeldung
Hinweis: Ihr Anmeldezeitpunkt innerhalb der Frist hat keine Auswirkungen auf die Platzvergabe (kein "first come, first served").
- Anmeldung von Fr 10.02.2023 14:00 bis Mi 31.05.2023 23:59
- Abmeldung bis Mi 31.05.2023 23:59
Details
max. 15 Teilnehmer*innen
Sprache: Deutsch
Lehrende
Termine (iCal) - nächster Termin ist mit N markiert
The course is structured as a block seminar. Each of the six days will be a full course day. The introduction to lipidomics and the course will be online on June 5th followed by two laboratory days on June 6th and 7th. Data analysis and interpretation will be introduced on June 12-14th. Details will be provided after the registration is closed.
- Dienstag 13.06. 10:00 - 18:00 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42
- Mittwoch 14.06. 10:00 - 18:00 Seminarraum 3 Organische Chemie 1OG Boltzmanngasse 1
Information
Ziele, Inhalte und Methode der Lehrveranstaltung
Lipidomics is the science that deals with the concentration-dependent description of hydrophobic biomolecules in space and time in a specific system. You will be taught one of the most practical approaches to achieve this goal. This course focuses on LC-MS based lipidomics. However, this course will also deliver basic concepts how to identify small molecules, which you can also apply in other fields of analytical chemistry. In this course the following topics might be presented or worked out together: lipid structure and function, nomenclature of lipids, extraction and sample preparation, LC-MS lipidomics, evaluation strategies for identification and quantification. Critical examination and scientific discussion of research results.
Art der Leistungskontrolle und erlaubte Hilfsmittel
We will judge your coursework and commitment. At the end of the course, you must present your lab results in a short presentation.
Mindestanforderungen und Beurteilungsmaßstab
Basic knowledge in data interpretation and statistics, concepts of mass spectrometry (lecture on mass spectrometry).
Prüfungsstoff
Literatur
Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics (doi: 10.1194/jlr.D700041-JLR200 )
Top-down lipidomic screens by multivariate analysis of high-resolution survey mass spectra.( doi: 10.1021/ac062455y)
Bottom-up shotgun lipidomics by higher energy collisional dissociation on LTQ Orbitrap mass spectrometers.( doi: 10.1021/ac102505f)
Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome.( doi: 10.1182/blood-2017-12-822890.)
Top-down lipidomic screens by multivariate analysis of high-resolution survey mass spectra.( doi: 10.1021/ac062455y)
Bottom-up shotgun lipidomics by higher energy collisional dissociation on LTQ Orbitrap mass spectrometers.( doi: 10.1021/ac102505f)
Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome.( doi: 10.1182/blood-2017-12-822890.)
Zuordnung im Vorlesungsverzeichnis
CH-SAS-06,BC CHE II-1, Design
Letzte Änderung: Mi 05.04.2023 13:29