300099 SE Advanced Topics in Evolutionary Reproductive Biology (2024S)
Prüfungsimmanente Lehrveranstaltung
Labels
VOR-ORT
An/Abmeldung
Hinweis: Ihr Anmeldezeitpunkt innerhalb der Frist hat keine Auswirkungen auf die Platzvergabe (kein "first come, first served").
- Anmeldung von Do 08.02.2024 14:00 bis Do 22.02.2024 18:00
- Abmeldung bis Fr 15.03.2024 18:00
Details
max. 12 Teilnehmer*innen
Sprache: Englisch
Lehrende
Termine (iCal) - nächster Termin ist mit N markiert
the meeting on 3/5/24 will be hybrid
the meeting on 3/19/24 is cancelled due to travel by the instructors
all the other meetings will be in person
Dienstag
05.03.
15:00 - 16:30
Hybride Lehre
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
09.04.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
16.04.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
23.04.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
30.04.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
07.05.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
14.05.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
N
Dienstag
21.05.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
28.05.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
04.06.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
11.06.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
18.06.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Dienstag
25.06.
15:00 - 16:30
Seminarraum 1.7, Biologie Djerassiplatz 1, 1.010, Ebene 1
Information
Ziele, Inhalte und Methode der Lehrveranstaltung
Art der Leistungskontrolle und erlaubte Hilfsmittel
The format will be a mix of short lectures from the instructors and mostly group discussions based on mandatory readings. Each student is expected to provide a short summary and reaction to the reading.
Mindestanforderungen und Beurteilungsmaßstab
Grades are based on participation and a brief essay on the topic of the seminar.
Prüfungsstoff
see above
Literatur
Papers will be posted at the begin of the semester. The participants of the seminar will be able to propose literature for discussion in addition to that offered by the seminar lead.
Zuordnung im Vorlesungsverzeichnis
MES5, MZO W3, MZO4
Letzte Änderung: Fr 02.02.2024 09:46
Instructors: Günter P. Wagner & Mihaela PavličevBackground: viviparity and a long-lasting physiological connection between the embryo/fetus and the mother is a key features of eutherian (so-called placental) mammals. Even though viviparity in the broad sense has evolved many times in animals, the mammalian form of viviparity is special in terms of the level of anatomical and cell biological intimacy of that relationship. It is also a highly unlikely arrangement that raises a host of biological paradoxa. Not the least of which is the immunological paradox, first articulated by Paul Medawar in 1952: why is the fetus not attacked by the mother's adaptive immune system. But there are more, like the inflammation paradox etc. Hence the problem of explaining the evolution of mammalian pregnancy has to focus on the question how evolution overcame these paradoxa.What will we be discussing?
• What are the patterns of viviparity in vertebrates?
• The structure and evolution of the Fetal-Maternal-Interface.
• What are the principal paradoxa of mammalian pregnancy?
• How did evolution overcome the paradoxa of mammalian pregnancy?Structure of the Seminar:1. Introduction to viviparity, the broad strokes
2. Structure and evolution of the Fetal Maternal Interface (FMI)
3. Theories of the FMI
4. Attachment: the cell biological paradox
5. Implantation: the inflammation paradox I
6. Implantation: the inflammation paradox II
7. Placental bed formation: the tissue biological paradox
8. The immunological paradox I
9. The immunological paradox II
10. Decidua hypothesis 1:
11. Decidua hypothesis 2:
12. Progesterone – the hormone of pregnancy
13. Revisiting the theories of FMIThe format will be a mix of short lectures from the instructors and mostly group discussions based on mandatory readings. Each student is expected to provide a short summary and reaction to the reading.
Grades are based on participation and a brief essay on the topic of the seminar.