Universität Wien

300217 UE Exercises in Population Genetics (2024W)

5.00 ECTS (3.00 SWS), SPL 30 - Biologie
Prüfungsimmanente Lehrveranstaltung

An/Abmeldung

Hinweis: Ihr Anmeldezeitpunkt innerhalb der Frist hat keine Auswirkungen auf die Platzvergabe (kein "first come, first served").

Details

max. 14 Teilnehmer*innen
Sprache: Englisch

Lehrende

Termine

Freitag 13:15-16:15

Note that as a one-time exception, the class on 4th October will take place virtually. Video link to be sent later by email.
All other classes will take place in person at seminar room 16, Oskar-Morgenstern-Platz 1 (3rd floor)

Oct 4: RK Basics of R (virtual)
Oct 11: HS Basics: distributions and statistics
Oct 18: HS Hardy-Weinberg testing
Oct 25: HS Deterministic Models
Nov 1: Public Holiday
Nov 8: RK Sampling, stochastic models, WF simulations
Nov 15: RK Sequence data
Nov 22: HS Drift with Selection: Transition matrices
Nov 29: RK Coalescent Simulations
Dec 6: HS Coalescent Simulations 2
Dec 13: RK Quantitative Genetics
Dec 18 to Jan 6: Winter Break
Jan 10: RK Neutrality Tests
Jan 17: HS Simulating quantitative traits


Information

Ziele, Inhalte und Methode der Lehrveranstaltung

Content:
Introduction to R and R graphics (ggplot2), Wright Fisher simulations, Coalescent simulations, application of neutrality tests, basic handling of NGS data, simulations of quantitative traits

Pre-requisites: basic knowledge of R and of the UNIX command line

Goals:
Students are familiar with the R programming language and commonly used tools in population genetics (MS, PAML, alignment tools). The students are able to simulate neutral and selective processes in populations. They can apply widely used neutrality tests to genome scale data.

Art der Leistungskontrolle und erlaubte Hilfsmittel

continuous assessment based on homework and in-class presentations

Mindestanforderungen und Beurteilungsmaßstab

minimal requirement: good understanding of key concepts taught in the lecture and the exercises

Prüfungsstoff

content of lecture and exercises

Literatur

Suggested reading:
Hedrick, Genetics of Populations, Jones and Bartlett
Crawley, Statistics: An Introduction Using R, Wiley
Barrett, Linux Pocket Guide: Essential Commands, Reilly
Paradis, R for beginners (available online from CRAN)

Zuordnung im Vorlesungsverzeichnis

MES1

Letzte Änderung: Sa 05.10.2024 20:06