300256 VO Molecular Basis of Bacterial Infections (2007W)

In this lecture series, an overview of the molecular mechanisms involved in the pathogenicity of gram-negative and gram-positive bacteria will be presented. The following topics will be addressed: bacterial diseases and antibiotic therapy: general aspects / pathogenesis of intracellular pathogens (Listeria, Shigella, Salmonella, Yersinia) / pathogenesis of gram-positive bacteria (Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus) / biofilm formation / bacterial appendages, virulence factors and toxins / protein secretion systems / regulation of virulence factor expression / quorum sensing-cell to cell communication / regulatory RNAs / regulatory proteolysis