Universität Wien

301450 VO Makromolekulare Kristallographie (2020S)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie

An/Abmeldung

Hinweis: Ihr Anmeldezeitpunkt innerhalb der Frist hat keine Auswirkungen auf die Platzvergabe (kein "first come, first served").

Details

Sprache: Englisch

Prüfungstermine

Lehrende

Termine

SR- VBC5, 1030 Wien
Termine jeweils 16.00 - 19.00 Uhr
20., 22., 24. 4.
27., 29.4.
4. - 8.5.2020


Information

Ziele, Inhalte und Methode der Lehrveranstaltung

The following topics will be covered the major topic of macromolecular crystallography and will provide students with a comprehensive overview of all the steps required to generate a three-dimensional structural information on biological macromolecules:
* sources of X-rays
* crystallisation techniques
* symmetry (point groups, space groups), unit cell, Bravais lattice
* scattering of X-rays, atomic form factor, structure factor
* waves, diffraction of molecules and crystals, Fourier transform; electron density
* set-up of MX diffraction experiment and detectors
* methods for solution of phase problem: molecular replacement, multiple isomorphous replacement, multi-wavelength anomalous dispersion
* density modification techniques
* structure refinement, structure validation and analysis

Art der Leistungskontrolle und erlaubte Hilfsmittel

Oral or written exam, depending on the number of students.
Oral exam in Zoom or written digital exam.

Mindestanforderungen und Beurteilungsmaßstab

Attendance and active participation during the lecture course, >60% correct answers of exam for passing grade.
Assessment criteria:
100-90%: excellent (1)
89-80%: good (2)
79-70%: satisfactory (3)
69-60%: sufficient (4)
< 59%: insufficient (5)

Prüfungsstoff

Contents of the lectures as given in the course lecture notes and handouts available on the Moodle.

Literatur

Will be provided by the lecturer in the first lecture.

Zuordnung im Vorlesungsverzeichnis

MMB II-2, MMB W-2, MMEI III, CHE II-6

Letzte Änderung: Mi 19.08.2020 07:49