Universität Wien
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301463 VO Biophysikalische Chemie der Makromoleküle (2025S)

Strukturbiologie

3.00 ECTS (2.00 SWS), SPL 30 - Biologie
Mi 07.05. 13:15-15:15 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien

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Details

Sprache: Englisch

Prüfungstermine

Lehrende

Termine (iCal) - nächster Termin ist mit N markiert

The lectures will be on Wednesdays at 13:15, in person, no recordings provided:
7.5. Thermodynamics (Robert Konrat)
14.5. Dynamic and kinetic aspects (Georg Kontaxis)
21.5. Folding and polymer theory (Bojan Zagrovic)
28.5. Biophysical Chemistry of Proteins (Thomas Leonard)
4.6. Biophysical Chemistry Nucleic Acids (Sebastian Falk)
11.6. Biophysical Chemistry of lipids (Anton Polyansky)
18.6. Macromolecular interactions and specificity of recognition (Arthur Sedivy)

Exams:

Tue at 9:00-10:30 24.6, 16.9 and 21.10.2024

  • Mittwoch 14.05. 13:15 - 15:15 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Mittwoch 21.05. 13:15 - 15:15 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Mittwoch 28.05. 13:15 - 15:15 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Mittwoch 04.06. 13:15 - 15:15 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Mittwoch 11.06. 13:15 - 15:15 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Mittwoch 18.06. 13:15 - 15:15 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien

Information

Ziele, Inhalte und Methode der Lehrveranstaltung

This lecture course is aimed at students at the master level and covers the physico-chemical description of biological macromolecules, which is relevant for their function. In the course of this structure and dynamic behavior of biopolymers are covered. The central topics that will be discussed include: governing principles of conformational organization of biomolecules, biomolecular function and dynamic behavior. They are explained in terms of molecular driving forces, and related to basic (bio-)physical principles of thermodynamics and kinetics and polymer theory through a mathematical description. The aim of this course is to give students a fundamental understanding of the basics of molecular biophysics in terms of first principles. Emphasis is put on a consistent quantitative description of the biophysical phenomena. The course is held by different lecturers which will cover the subjects of their expertise.
The central topics that will be discussed include: advanced principles of conformational organization of biomolecules, biomolecular kinetics and thermodynamics, molecular driving forces, polymer theory and principles of macromolecular interactions.

Art der Leistungskontrolle und erlaubte Hilfsmittel

Oral or written exam, depending on the number of students.
Oral exam in Zoom or written exam.

Mindestanforderungen und Beurteilungsmaßstab

Attendance and active participation during the lecture course, >60% correct answers of exam for passing grade.
Assessment criteria:
100-90%: excellent (1)
89-80%: good (2)
79-70%: satisfactory (3)
69-60%: sufficient (4)
< 59%: insufficient (5)

Prüfungsstoff

Contents of the lectures as given in the course lecture notes and handouts available on the Moodle.

Literatur

The MAJOR SOURCE for this lecture series is the book:
John Kuriyan, Boyana Konforti, David Wemmer - The Molecules of Life: Physical and Chemical Principles

Additional reading:
K Dill -Molecular Driving Forces; Cantor & Schimmel -Biophysical Chemistry

Zuordnung im Vorlesungsverzeichnis

MMB III-1a:, MMB iV:, MNEU V., M-WZB, MMEI III

Letzte Änderung: Fr 17.01.2025 15:47