Universität Wien

301618 VO+SE Strukturbiologie II (2020S)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie

An/Abmeldung

Hinweis: Ihr Anmeldezeitpunkt innerhalb der Frist hat keine Auswirkungen auf die Platzvergabe (kein "first come, first served").

Details

Sprache: Englisch

Prüfungstermine

Lehrende

Termine (iCal) - nächster Termin ist mit N markiert

Termine jeweils Do. 10.00 - 12.00 Uhr
Beginn: 05.3.2020
Lecture Hall /Dept. for Structural and Computational Biology
Campus Vienna Biocenter 5, 1030 Wien.
http://www.univie.ac.at/biolchem/location.html
Lecture notes are available on Moodle.

  • Donnerstag 05.03. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 19.03. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 26.03. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 02.04. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 23.04. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 30.04. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 07.05. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 14.05. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 28.05. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 04.06. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 18.06. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien
  • Donnerstag 25.06. 10:00 - 12:00 STB/Hörsaal B Campus Vienna Biocenter 5, 1030 Wien

Information

Ziele, Inhalte und Methode der Lehrveranstaltung

Thermodynamics - introduction
Thermodynamics - experimental determination of binding affinities with examples
Thermodynamics - protein folding/unfolding, differential scanning calorimetry
Analysis and validation of macromolecular 3D structures
Protein dynamics at different scales
Structural basis of allosteric regulation
Conformational selection versus induced fit
Periodic table of Protein complexes
The dark proteome intrinsically disordered proteins
Structural basis of affinity and specificity with examples
Reaction mechanisms as reaction kinetics

Art der Leistungskontrolle und erlaubte Hilfsmittel

Written digital exam.
Due to the Covid-19 measures, the exam will be held in SS 2020 in digital form provided in Moodle.

Mindestanforderungen und Beurteilungsmaßstab

Attendance and active participation during the lecture course, >60% correct answers of exam for passing grade.
Assessment criteria:
100-90%: excellent (1)
89-80%: good (2)
79-70%: satisfactory (3)
69-60%: sufficient (4)
< 59%: insufficient (5)

Prüfungsstoff

Contents of the lectures as given in the course lecture notes and handouts available on the Moodle.

Literatur

A list of possible textbooks will be presented in the first lecture. Additional references are given throughout the lectures.

Zuordnung im Vorlesungsverzeichnis

BMB 9

Letzte Änderung: Fr 12.05.2023 00:24