Universität Wien

323115 VU NMR for Drug Design - MPS5 (2023S)

2.00 ECTS (1.00 SWS), SPL 32 - Pharmazie
Prüfungsimmanente Lehrveranstaltung
Moodle

An/Abmeldung

Hinweis: Ihr Anmeldezeitpunkt innerhalb der Frist hat keine Auswirkungen auf die Platzvergabe (kein "first come, first served").

Details

Sprache: Englisch

Lehrende

Termine

ROOM: 2D313
BUILDING: Division of Pharmaceutical Chemistry, Josef-Holaubek-Platz 2;
TIME:10.00-12.00
DATES:
14.06
16.06
19.06
21.06
23.06
27.06
28.06

Information

Ziele, Inhalte und Methode der Lehrveranstaltung

Protein-ligand interactions are at the heart of drug discovery research. NMR spectroscopy is perfectly suited to identify and validate protein-ligand interactions. A large number of NMR experiments are available. They are very powerful, but may also have pitfalls and limitations.
In this lecture, we will present central experiments for NMR in drug discovery, and assess their strengths and reliabilities.
Furthermore, methods for subsequent characterization of the interaction such as quantitative KD determination, binding mode analysis, or structure determination will be covered if time allows.

Art der Leistungskontrolle und erlaubte Hilfsmittel

Active cooperation

Mindestanforderungen und Beurteilungsmaßstab

Basic knowledge of NMR
322052-1 -Basics of NMR Spectroscopy - M14

Prüfungsstoff

Discussed scientific topics in the field of practical aspects of NMR for Drug Design in the form of short seminars.

Literatur

Zuordnung im Vorlesungsverzeichnis

Letzte Änderung: So 11.06.2023 17:28