270038 VO Enzymes - reaction mechanisms and application in organic chemistry (2008W)

1.50 ECTS (1.00 SWS), SPL 27 - Chemie

Blocklehrveranstaltung in der ersten Semesterhälfte, 7.5 Doppelstunden; 1.5 ECTS.
Vorbesprechung (gemeinsam mit Vorlesung über Biosynthese) und Beginn für Vorlesung: Do 9. 10. 2008, 8.15, HS III.

Details

Language: German

Lecturers

Friedrich Hammerschmidt

Classes

Currently no class schedule is known.

Information

Aims, contents and method of the course

General informations on enzymes, methods of biotransformations, regeneration of cofactors, uses of oxidoreductases: enantioselective reductions and oxidations; oxidation reactions: enzymatic Bayer-Villiger oxidation, insertion of oxygen into C-H bond, dihydroxylation of aromatics; hydrolysis and condensation reactions catalysed by lipases and proteases: kinetic resolution of alcohols and amino acids; formation of C-C bonds: yeast-catalysed acyloin condensation, aldol reaction, synthesis of cyanohydrins; isopenicillin-N synthase: preparation of modified penicillins; underlying reaction mechanisms.
Required background: basic knowledge of organic chemistry and biochemistry.

Assessment and permitted materials

Minimum requirements and assessment criteria

Understanding of basic reaction mechanisms and importance and application of enzymes for the preparation of optically active compounds.

Examination topics

Reading list

Eigene Mitschrift.

Association in the course directory

BC-4,OC-3

Last modified: Fr 31.08.2018 08:55