270084 SE Medicinal Inorganic Chemistry (2024W)

The utilization of metals for health and healing dates back thousands of years. The intentional exploration of the structure and properties of specific inorganic complexes for medicinal purposes has significantly advanced in the last 50 years since the discovery of cisplatin. To date, cisplatin and its derivatives are used in more than 50% of chemotherapeutic treatments worldwide, highlighting the enormous potential of metal-based therapeutics. Within this lecture, the use of metal complexes for medicinal application is critically reviewed based on recent examples in the clinics and the literature.