270104 VO Supramolecular organic Chemistry (2023W)
Labels
Registration/Deregistration
Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
Details
Language: German
Examination dates
Wednesday
07.02.2024
Thursday
29.02.2024
15:00 - 18:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Friday
19.04.2024
15:00 - 18:00
Hörsaal 4 Chemie HP Währinger Straße 42
Lecturers
Classes (iCal) - next class is marked with N
Thursday
05.10.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Friday
06.10.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Thursday
12.10.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Thursday
19.10.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Thursday
09.11.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Friday
10.11.
14:00 - 16:00
Seminarraum 2 Währinger Straße 38 Dekanat 1. Stock
Tuesday
14.11.
15:00 - 17:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Friday
17.11.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Thursday
30.11.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Tuesday
05.12.
15:00 - 17:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Thursday
14.12.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Thursday
11.01.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Tuesday
16.01.
15:00 - 17:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Thursday
18.01.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Tuesday
23.01.
14:30 - 16:30
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Thursday
25.01.
14:00 - 16:00
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Tuesday
30.01.
14:30 - 16:30
Kleiner Hörsaal 3 Chemie Boltzmanngasse 1 HP
Information
Aims, contents and method of the course
Assessment and permitted materials
Written exam (100%). The candidate needs to reply to a series of questions scoring at least 50% to get the pass mark.
Minimum requirements and assessment criteria
A written exam with questions will be given and assessed. The questions will be centred around a series of examples from the literature and the candidate will be required to provide organic synthetic-driven and physical organic reasoning.
Examination topics
Basic concepts in self-assembly and self-organization, thermodynamics and kinetics of host-guest processes along with the main characterization techniques; complexation of neutral molecules in aqueous solution and their technological applications - sensors and drug delivery; non-covalent interactions involving aromatic rings; hydrogen-, halogen- and chalcogen-bonding interactions; dynamic covalent bonds; supramolecular polymers; Template effects & molecular self-assembly approach towards architectures in solutions (including molecular cages) and in the solid-state; basic concepts of crystal engineering; MOFs and COFs, gas storage, separation and sensing applications; applications of molecular recognition in catalysis and logic gates, including medical diagnostics, colorimetric and luminescent sensors; molecular machines, from simple catenanes and rotaxanes to more complex multi-station multi-stimuli responsive supramolecular systems; basic concepts of molecular recognition in biology, including cell architecture, biomolecular interactions, structure of essential building units, lipids, DNA/RNA, protein, sugar; natural Ion Channels, including peptide-based ion change, cation/anion complexation, cross-membrane ion channel; biotechnological applications (e.g. artificial enzyme design, live cell imaging, cellular import/drug delivery) based on the concepts of supramolecular chemistry.
Reading list
Most of the concepts in this module are covered in the primary literature and review papers that are given during the course. Some basic book text introducing to the concept:
Supramolecular Chemistry, J.-M. Lehn, 1995, VCH, Weinheim
Supramolecular Chemistry – Fundamentals and Applications, K. Ariga, T. Kunitake, 2006, Springer, Berlin
Supramolecular Chemistry (2nd Revised edition), J.-W. Steed, J. L. Atwood, 2009, Wiley
Supramolecular Chemistry, J.-M. Lehn, 1995, VCH, Weinheim
Supramolecular Chemistry – Fundamentals and Applications, K. Ariga, T. Kunitake, 2006, Springer, Berlin
Supramolecular Chemistry (2nd Revised edition), J.-W. Steed, J. L. Atwood, 2009, Wiley
Association in the course directory
CH-SYN-03
Last modified: Fr 12.04.2024 11:46
Once the basic principles have been covered, the course will move on to a discussion of principles and examples of solution, surface and solid-state self-assembled molecular species. Specifically, organic molecular receptors and metal-organic frameworks will be covered, with examples of their sensing and storage applications, before moving on to increasingly complex molecular logic-gates and molecular machines. Additionally, this course will go through the concepts of how nature exploits supramolecular chemistry to perform crucial biological events, such as nucleic acid- and protein- depending function and ion transport. For illustrative purposes, case studies will be illustrate and the students encouraged to think creatively whenever possible during the exercises sections. Usually a case-study is presented per lecture.