Universität Wien

270113 VO+SE Introduction to Bioinorganic Chemistry (2013W)

4.00 ECTS (4.00 SWS), SPL 27 - Chemie
Continuous assessment of course work

Beginn: 08.10.2013, Seminarraum 4 (Inst. f. Physikalische Chemie).
Die 08.10.2013 bis Die 26.11.2013 und Do 10.10.2013 bis Do 28.11.2013, 10-12 Uhr; Mi 09.10.2013 bis Mi 27.11.2013, 9-11 Uhr; Zusätzlich: Mo 14.10., 21.10. und 28.10.2013, 11-13 Uhr.

Details

Language: English

Lecturers

Classes

Currently no class schedule is known.

Information

Aims, contents and method of the course

An overview on the chemistry, biochemistry, and biology of metal ion - biomolecule interactions are given in the course. The role of the metal ion in biological systems is discussed partly as their functional roles and partly as their element group.
Essential metall ions and their evolution. Characterisation of the interactions of metal ions and biomolecules (amino acids, peptides, proteins, nucleic acids, nucleotides, carbohydrates, macrocycles). Unequally distributed electrolytes: The bioinorganic chemistry of the alkali and alkaline earth metal ions. Metal at the centre of photosynthesis.
Activation of small molecules in biology. Bioinorganic chemistry of dioxygen. Iron containing metalloenzymes and metalloproteins. The iron metabolism. Eelectron transfer proteins. Enzymatic catalysis of hydrolysis or condensation reactions: the bioinorganic chemistry of zinc(II). The metabolism of zinc(II).Other metal ions (Co, Mn, V, Cr, Mo) Toxic metal ions (Cd, Hg) an their detoxification. Metal compounds in medicine, chelate-therapy.

Assessment and permitted materials

The students are asked to prepare a short written project in a selected topic, what should be present in the form of oral communication too, what will be discussed by the group. The list of the topics is enclosed.

Minimum requirements and assessment criteria

Examination topics

Reading list

1. W. Kaim, B. Schwederski: Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, (Wiley, Chichester, 1994); 2. S. J. Lippard, J. M. Berg: Principles of Bioinorganic Chemistry, University Science Books, Mill Valley, California, 1994; 3. R. R. Crichton: Biological Inorganic Chemistry An Introduction, Elsevier, Amsterdam, 2008; 4. J. A. Cowan: Inorganic Biochemistry, An Introduction, (VCH, New York, 1993).

Association in the course directory

AC-1

Last modified: Fr 31.08.2018 08:55