Universität Wien
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270127 VO Organic Chemical Methods (2019W)

in Molecular Biology and Biochemistry

2.50 ECTS (2.00 SWS), SPL 27 - Chemie
Moodle

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Details

max. 50 participants
Language: German

Examination dates

Lecturers

Classes

each Wednesday, 06:15 - 07:45 p.m., HS 3
first lecture 9th October 2019

Information

Aims, contents and method of the course

Requirements: Background knowledge in organic chemistry and biological chemistry (Bachelor) (students of chemistry or molecular biology or microbiology and genetics)
1st Part: Detailed presentation of organic chemical methods well established and applied in biochemistry and molecular biology: Peptide synthesis, oligonucleotide synthesis, selective preparation of different types of conjugates (labeling) of biopolymers and organic chemical aspects of protein sequencing, analysis of glycoconjugates and DNA sequencing. 2nd Part: Specific modifications of biologically relevant molecules to solve biochemical relevant questions discussed as specific examples from new literature. In the centre of this discussion are not the organic syntheses in detail but the overall strategies applied. The literature examples selected belong to the following themes: Lipopeptides and -proteins in signal transduction, immunological applications of peptides (synthetic vaccines), modification of nucleic acids, modified proteins, structure activity relationships for enzymes (inhibitors) and receptors.
learning goals: Possibilities and restrictions for the application of organic chemical methods in molecular biology and biochemistry research. Development of interdisciplinary strategies for problem solving in these areas.

For more informations see: http://homepage.univie.ac.at/daniel.krois/DKVO.html

Assessment and permitted materials

assessment (LP): oral examination, use of the discussed research papers

Minimum requirements and assessment criteria

Examination topics

all presented subject matter of the course

Reading list

Handouts (see moodle)
Textbook: D.Krois, Organisch-chemische Methoden, Springer Spektrum, Heidelberg, 2017.

Association in the course directory

BC-4, OC-3, CHE II-4

Last modified: Tu 24.11.2020 10:29