Assessment and permitted materials
Written exam 60%
Minimum requirements and assessment criteria
Basic concepts in self-assembly and self-organization, thermodynamics and kinetics of host-guest processes along with the main characterization techniques; complexation of neutral molecules in aqueous solution and their technological applications - sensors and drug delivery; non-covalent interactions involving aromatic rings; hydrogen-, halogen- and chalcogen-bonding interactions; dynamic covalent bonds; supramolecular polymers; Template effects & molecular self-assembly approach towards nanostructures in solutions (including molecular cages) and in the solid-state; basic concepts of crystal engineering; MOFs and COFs, gas storage, separation and sensing applications; applications of molecular recognition in logic gates, including medical diagnostics, colorimetric and luminescent sensors; molecular machines, from simple catenanes and rotaxanes to more complex multi-station multi-stimuli responsive supramolecular systems; basic concepts of molecular recognition in biology, including cell architecture, biomolecular interactions, structure of essential building units, lipids, DNA/RNA, protein, sugar; natural Ion Channels, including peptide-based ion change, cation/anion complexation, cross-membrane ion channel; biotechnological applications (e.g. artificial enzyme design, live cell imaging, cellular import/drug delivery) based on the concepts of supramolecular chemistry.
Most of the concepts in this module are covered in the primary literature and review papers that are given during the course.
Supramolecular Chemistry, J.-M. Lehn, 1995, VCH, Weinheim
Supramolecular Chemistry – Fundamentals and Applications, K. Ariga, T. Kunitake, 2006, Springer, Berlin
Supramolecular Chemistry (2nd Revised edition), J.-W. Steed, J. L. Atwood, 2009, Wiley