Universität Wien
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270185 VO Concepts of Bioinorganic Chemistry (2022S)

4.00 ECTS (2.00 SWS), SPL 27 - Chemie
Moodle

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Details

Language: German

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

  • Wednesday 27.04. 13:00 - 14:30 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42
  • Wednesday 04.05. 13:00 - 14:30 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42
  • Wednesday 11.05. 13:00 - 14:30 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42
  • Wednesday 18.05. 13:00 - 14:30 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42
  • Tuesday 24.05. 13:30 - 15:00 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42
  • Wednesday 01.06. 13:00 - 14:30 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42
  • Wednesday 08.06. 13:00 - 14:30 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42
  • Wednesday 15.06. 13:00 - 14:30 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42
  • Wednesday 22.06. 13:00 - 14:30 Seminarraum 4 Institut Physikalische Chemie HP Währinger Straße 42

Information

Aims, contents and method of the course

Inorganic species and metal ions are of fundamental importance for all living organisms. They play a wide variety of roles, ranging from signal transduction, structural design in proteins and skeletons, electron transfer and oxygen transport to the catalysis of complex reactions. Through the precise combination of protein matrix, architecture of the active site and choice of metal ion, nature succeeds in realizing a wide variety of reactions such as Lewis acid catalysis, organometallic reactions but also oxygen activation with substrate turnover. Despite these complex systems, these reactions follow general and complex chemical concepts. These concepts are the focus of the lecture and will be elaborated on the basis of selected bioinorganic processes and proteins. This is done with the aim that more complex bioinorganic relationships can be easily derived and understood. The lecture concludes with an outline on how these concepts can be applied to use inorganic species in medicine, either for imaging or as therapeutics.

Assessment and permitted materials

Final oral exam, approx. 30 min., at a date agreed individually with the course instructor.

Minimum requirements and assessment criteria

To achieve a passing grade, 50% of the questions must be answered satisfactorily.

Examination topics

Lecture notes and all content covered in the course.

Reading list

To achieve the above learning objectives, the following literature is recommended: textbooks of bioinorganic chemistry and coordination chemistry, e.g.:
• W. Kaim, B. Schwederski, Bioanorganische Chemie, 4. Auflage, Teubner, Wiesbaden, 2005
• W. Kaim, B. Schwederski, Axel Klein, Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, 2. Auflage, Wiley, West Sussex, 2013
• S. J. Lippard, J. M. Berg, Bioanorganische Chemie, Spektrum Akademischer Verlag, Berlin, 1995
• S. Herres-Pawlis, P. Klüfers, Bioanorganische Chemie, Wiley-VCH, Weinheim, 2017
• Ausgewählte Kapitel: Sigel, Sigel, Sigel (Eds), Metal Ions in Life Science (MILS) Serie (Band 1-15), Wiley, De Gruyter, Springer, RSC Publishing, 2007 - now

Association in the course directory

EF-1, EF-2, EF-3

Last modified: Mo 31.10.2022 13:09