270188 VO+UE Supramolecular Chemistry (2020W)
Continuous assessment of course work
Labels
Registration/Deregistration
Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
- Registration is open from We 30.09.2020 08:00 to Th 15.10.2020 12:00
- Deregistration possible until Th 15.10.2020 12:00
Details
max. 100 participants
Language: English
Lecturers
Classes (iCal) - next class is marked with N
Thursday
05.11.
14:00 - 15:30
Digital
Tuesday
10.11.
15:00 - 16:30
Digital
Thursday
12.11.
14:00 - 15:30
Digital
Thursday
19.11.
14:00 - 15:30
Digital
Tuesday
24.11.
15:00 - 16:30
Digital
Thursday
26.11.
14:00 - 15:30
Digital
Thursday
03.12.
14:00 - 15:30
Digital
Thursday
10.12.
14:00 - 15:30
Digital
Tuesday
15.12.
15:00 - 16:30
Digital
Thursday
17.12.
14:00 - 15:30
Digital
Thursday
07.01.
14:00 - 15:30
Digital
Tuesday
12.01.
15:00 - 16:30
Digital
Thursday
14.01.
14:00 - 15:30
Digital
Thursday
21.01.
14:00 - 15:30
Digital
Thursday
28.01.
14:00 - 15:30
Digital
Information
Aims, contents and method of the course
Assessment and permitted materials
Written exam 60%
Coursework 40%
Coursework 40%
Minimum requirements and assessment criteria
Examination topics
Basic concepts in self-assembly and self-organization, thermodynamics and kinetics of host-guest processes along with the main characterization techniques; complexation of neutral molecules in aqueous solution and their technological applications - sensors and drug delivery; non-covalent interactions involving aromatic rings; hydrogen-, halogen- and chalcogen-bonding interactions; dynamic covalent bonds; supramolecular polymers; Template effects & molecular self-assembly approach towards nanostructures in solutions (including molecular cages) and in the solid-state; basic concepts of crystal engineering; MOFs and COFs, gas storage, separation and sensing applications; applications of molecular recognition in logic gates, including medical diagnostics, colorimetric and luminescent sensors; molecular machines, from simple catenanes and rotaxanes to more complex multi-station multi-stimuli responsive supramolecular systems; basic concepts of molecular recognition in biology, including cell architecture, biomolecular interactions, structure of essential building units, lipids, DNA/RNA, protein, sugar; natural Ion Channels, including peptide-based ion change, cation/anion complexation, cross-membrane ion channel; biotechnological applications (e.g. artificial enzyme design, live cell imaging, cellular import/drug delivery) based on the concepts of supramolecular chemistry.
Reading list
Most of the concepts in this module are covered in the primary literature and review papers that are given during the course.
Supramolecular Chemistry, J.-M. Lehn, 1995, VCH, Weinheim
Supramolecular Chemistry – Fundamentals and Applications, K. Ariga, T. Kunitake, 2006, Springer, Berlin
Supramolecular Chemistry (2nd Revised edition), J.-W. Steed, J. L. Atwood, 2009, Wiley
Supramolecular Chemistry, J.-M. Lehn, 1995, VCH, Weinheim
Supramolecular Chemistry – Fundamentals and Applications, K. Ariga, T. Kunitake, 2006, Springer, Berlin
Supramolecular Chemistry (2nd Revised edition), J.-W. Steed, J. L. Atwood, 2009, Wiley
Association in the course directory
OC-2
Last modified: Fr 12.05.2023 00:22
Once the basic principles have been covered, the course will move on to a discussion of principles and examples of solution, surface and solid-state self-assembled molecular species. Specifically, organic molecular receptors and metal-organic frameworks will be covered, with examples of their sensing and storage applications, before moving on to increasingly complex molecular logic-gates and molecular machines. Additionally, this course will go through the concepts of how nature exploits supramolecular chemistry to perform crucial biological events, such as nucleic acid- and protein- depending function and ion transport. For illustrative purposes, case studies will be illustrate and the students encouraged to think creatively whenever possible during the exercises sections. Usually a case-study is presented per lecture.