300095 VU Metabolic network reconstruction and analysis (2023S)
Continuous assessment of course work
Labels
Registration/Deregistration
Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
- Registration is open from Th 09.02.2023 08:00 to Th 23.02.2023 18:00
- Deregistration possible until We 15.03.2023 18:00
Details
max. 25 participants
Language: English
Lecturers
Classes (iCal) - next class is marked with N
- Thursday 02.03. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Thursday 09.03. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Thursday 16.03. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Thursday 23.03. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Thursday 30.03. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Thursday 20.04. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Thursday 27.04. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Thursday 04.05. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Tuesday 09.05. 13:15 - 16:30 Seminarraum 1.1 PC, Biologie Djerassiplatz 1, 1.003, Ebene 1
- Thursday 11.05. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Thursday 25.05. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Wednesday 31.05. 13:15 - 16:30 Seminarraum 1.1 PC, Biologie Djerassiplatz 1, 1.003, Ebene 1
- Thursday 01.06. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Wednesday 07.06. 13:15 - 16:30 Seminarraum 1.1 PC, Biologie Djerassiplatz 1, 1.003, Ebene 1
- Thursday 15.06. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Wednesday 21.06. 13:15 - 16:30 Seminarraum 1.1 PC, Biologie Djerassiplatz 1, 1.003, Ebene 1
- Thursday 22.06. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
- Thursday 29.06. 09:45 - 11:15 Seminarraum 1.2, Biologie Djerassiplatz 1, 1.004, Ebene 1
Information
Aims, contents and method of the course
Assessment and permitted materials
- Written exam (50%)
- Solutions of computer exercises (50%)
- Solutions of computer exercises (50%)
Minimum requirements and assessment criteria
All partial evaluations must be positive to pass the course. Minimum score to pass is 50% in total.
Examination topics
In the exam, students need to show that they are able to constructively apply and discuss the methods taught in the course.
Reading list
Bernhard O. Palsson: Systems Biology. Constraint-based Reconstruction and Analysis. Cambridge University Press, 2015
Costas D. Maranas, Ali R. Zomorrodi: Optimization Methods in Metabolic Networks. John Wiley & Sons, 2016
Costas D. Maranas, Ali R. Zomorrodi: Optimization Methods in Metabolic Networks. John Wiley & Sons, 2016
Association in the course directory
MES3, M-WZB, MEC-9, MBO 7
Last modified: Fr 05.05.2023 09:28
They will be able to perform a basic computational analysis of such models, and will be able to use them for the prediction of metabolic fluxes with constraint- and optimization-based methods.
They can construct metabolic network models from genetic sequence data and suitable enzyme/reaction databases with suitable software tools.ContentsStructure and properties of metabolic network models
Working with metabolic network models: flux balance analysis, flux variability analysis
Genome-scale models
Reconstruction of models from genetic data