300308 VO Human Evolutionary Genetics: genomic, genes, diseases (2021S)

REMOTE

Moodle

Registration/Deregistration

Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).

Details

Language: English

Examination dates

Lecturers

Helmut Schaschl

Classes (iCal) - next class is marked with N

Due to the unpredictable Corona measures taken by the government, it can be assumed that at least the lectures in March and partly in April will only take place online using Collaborate in Moodle.

Monday 01.03. 15:00 - 16:30 Digital
Monday 08.03. 15:00 - 16:30 Digital
Monday 15.03. 15:00 - 16:30 Digital
Monday 22.03. 15:00 - 16:30 Digital
Monday 12.04. 15:00 - 16:30 Hybride Lehre
Hörsaal 2 UZA 1 Biozentrum 2.249 1.OG
Monday 19.04. 15:00 - 16:30 Hybride Lehre
Hörsaal 2 UZA 1 Biozentrum 2.249 1.OG
Monday 26.04. 15:00 - 16:30 Hybride Lehre
Hörsaal 2 UZA 1 Biozentrum 2.249 1.OG
Monday 03.05. 15:00 - 16:30 Hybride Lehre
Hörsaal 2 UZA 1 Biozentrum 2.249 1.OG
Monday 10.05. 15:00 - 16:30 Hybride Lehre
Hörsaal 2 UZA 1 Biozentrum 2.249 1.OG
Monday 17.05. 15:00 - 16:30 Digital
Monday 31.05. 15:00 - 16:30 Hybride Lehre
Hörsaal 2 UZA 1 Biozentrum 2.249 1.OG
Monday 07.06. 15:00 - 16:30 Hybride Lehre
Hörsaal 2 UZA 1 Biozentrum 2.249 1.OG
Monday 14.06. 15:00 - 16:30 Hybride Lehre
Hörsaal 2 UZA 1 Biozentrum 2.249 1.OG
Monday 21.06. 15:00 - 16:30 Hybride Lehre
Hörsaal 2 UZA 1 Biozentrum 2.249 1.OG
Monday 28.06. 15:00 - 16:30 Hybride Lehre

Information

Aims, contents and method of the course

The aim of this lecture is to provide students with knowledge and a good understanding of the scientific field of human genetics. The lectures will also prepare students in particular to understand how different evolutionary forces influence the human genome. Students learn about the key concepts of human evolutionary genetics and gain insights into how genetics can be used to elucidate the phenotypic traits such as diseases, immune defences and behaviour.
The first part of the lectures introduces students to the structure of the human genome, the key aspects of chromosome biology, and autosomal, mtDNA and X/Y-linked inheritance; the basis of gene functions and the role of epigenetics in gene regulation. In the second part, students will be briefly introduced to the state-of-the-art methods used in human genomics. The third part of the lectures aims to provide an understanding of the key concepts of human evolutionary genetics, population genetics, and molecular anthropology. Students gain insight into how different evolutionary processes affect genetic diversity and learn how these concepts are used to understand genetic diversity at both an individual and population level. In the fourth part, students will gain understanding how human genomic variation can directly or indirectly affect the risk to develop diseases, contribute to host defence, and influences human behaviours. (Research-focused lectures providing case-studies).
Teaching and learning methods: Lectures, handouts, and presentations (PowerPoint slides will be provided on Moodle).

Assessment and permitted materials

Depending on the government's Corona measures, the exam is either held digitally (Moodle) or as attendance exam.

Minimum requirements and assessment criteria

Student should gain knowledge and understanding:
i) the structure of the human genome, the basics of chromosome biology and heredity;
ii) the basics of gene function, regulation, and transcription;
iii) the role of epigenetic modification in gene regulation;
iv) molecular methods used in human genetics/genomics;
v) the key concepts of human evolutionary genetics and population genetics;
vi) human genomic variation and function in human health, disease and behaviour
vii) applying the gained knowledge to research questions/problems.
For a positive grade, at least 50% of the exam questions must be answered correctly.

Examination topics

Lectures, handouts, and presentations (course content).

Textbooks:
Human Evolutionary Genetics (2013, 2nd ed.). Mark A. Jobling et al.
An Introduction to Molecular Anthropology (2016). Mark Stoneking.
Human Molecular Genetics (2018, 5th ed.). Tom Strachan & Andrew Read

Reading list

Human Evolutionary Genetics
Mark A. Jobling, Edward Hollox , Mathew Hurles, Toomas Kivisild, Chris Tyler-Smith.
Publication Date: June 25, 2013 | ISBN-10: 0815341482 | ISBN-13: 978-0815341482 | Edition: 2

An Introduction to Molecular Anthropology
Mark Stoneking
ISBN: 978-1-118-06162-6 December 2016 Wiley-Blackwell

Human Molecular Genetics (5th ed.)
Tom Strachan & Andrew Read
Publication Date: December, 2018 | · ISBN-13: 9780815345893 | Edition: 5

The Princeton Guide to Evolution
Jonathan B. Losos (editor in chief), David A. Baum, Douglas J. Futuyma, Hopi E. Hoekstra, Richard E. Lenski, Allen J. Moore, Catherine L. Peichel, Dolph Schluter & Michael C. Whitlock (editors). Publication Date: 2013, ISBN: 9780691149776. eBook ISBN: 9781400848065

Association in the course directory

UF BU 10, BAN 2

Last modified: Fr 12.05.2023 00:23