300618 VO+SE Structural Biology (Macromolecular Crystallography) (2013S)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie

Lectures will be every Monday and Friday at 11 - 13 h on the following dates:
13.5.
17.5.
24.5.
27.5.
31.5
3.6.
7.6.
10.6
Lecture Hall A, Dept. for Structural and Computational Biology
Campus Vienna Biocenter 5, 1030 Wien.
http://www.univie.ac.at/biolchem/location.html

Lecture notes are available on Moodle.

Moodle

Details

Language: English

Examination dates

Lecturers

Kristina Djinovic-Carugo

Classes

Currently no class schedule is known.

Information

Aims, contents and method of the course

Lecture notes are available on Moodle.

The following topics will be covered:
* sources of X-rays
* crystallisation techniques
* symmetry (point groups, space groups), unit cell, Bravais lattice
* scattering of X-rays, atomic form factor, structure factor
* waves, diffraction of molecules and crystals, Fourier transform; electron density
* set-up of MX diffraction experiment and detectors
* methods for solution of phase problem: molecular replacement, multiple isomorphous replacement, multi-wavelength anomalous dispersion
* density modification techniques
* structure refinement and analysis.

Assessment and permitted materials

Minimum requirements and assessment criteria

Examination topics

Reading list

Association in the course directory

B-BMB 2, BMB 10, M125

Last modified: Mo 07.09.2020 15:44