Universität Wien
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300618 VO+SE Structural Biology (Macromolecular Crystallography) (2014S)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie

Ternine jeweils:Di. 15.30 - 17.00 Uhr und Do. 16.30 - 18.00 Uhr
Beginn: 4.3.2014
Lecture Hall B, Dept. for Structural and Computational Biology
Campus Vienna Biocenter 5, 1030 Wien.
http://www.univie.ac.at/biolchem/location.html
Lecture notes are available on Moodle.

Details


Information

Aims, contents and method of the course

Lecture notes are available on Moodle.

The following topics will be covered:
* sources of X-rays
* crystallisation techniques
* symmetry (point groups, space groups), unit cell, Bravais lattice
* scattering of X-rays, atomic form factor, structure factor
* waves, diffraction of molecules and crystals, Fourier transform; electron density
* set-up of MX diffraction experiment and detectors
* methods for solution of phase problem: molecular replacement, multiple isomorphous replacement, multi-wavelength anomalous dispersion
* density modification techniques
* structure refinement and analysis.

Assessment and permitted materials

Minimum requirements and assessment criteria

Examination topics

Reading list


Association in the course directory

B-BMB 2, CHE II-6

Last modified: Mo 07.09.2020 15:44