300681 VO Elective Course in Molecular Medicine (2007W)
Molecular Mechanisms of Multidrug resistance in Cancer and Anti-Infective Therapy
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BZB/Ebene 2, 1030, Dr. Bohr-Gasse 9
Department für Med.Biochemie der Med.Uni.Wien
Anmeldungen, Beginn- u. Vorbesprechungstermine siehe auch Studentenseite der Institute Dr. Bohr-Gasse: http://www.students.mfpl.ac.at/
auch für Dissertant/Innen geeignet
Department für Med.Biochemie der Med.Uni.Wien
Anmeldungen, Beginn- u. Vorbesprechungstermine siehe auch Studentenseite der Institute Dr. Bohr-Gasse: http://www.students.mfpl.ac.at/
auch für Dissertant/Innen geeignet
Details
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Aims, contents and method of the course
The class deals with the following topics: (1), the molecular basis and diagnosis of multidrug resistance (MDR) in anticancer therapy mediated by ATP-binding Cassette (ABC) membrane transporters. (2), The causes and mechanisms of multiple antibiotic, antifungal and antiparasitic drug resistance phenomena in infectious disease therapy. (3), Strategies to overcome MDR caused by ABC-mediated increased drug efflux. (4) Molecular mechanisms of genetic diseases caused by ABC genes implicated in cystic fibrosis, intrahepatic cholestasis, andrenoleukodystrophy, hypercholesterinemia through defects in HDL assembly, sitosterolemia, defects in hepatic detoxification.
Assessment and permitted materials
Minimum requirements and assessment criteria
Examination topics
Reading list
Association in the course directory
MMB IV-2, M210
Last modified: Fr 31.08.2018 08:57