Universität Wien

300693 VO Macromolecular Crystallography (2010W)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie

SR/Dept. Structural and Computational Biology, Campus Vienna Biocenter /5, 1030 Wien.

Lectures will be on Wednesdays at 9:30 and on Fridays at 9:00h

Lecture notes can be downloaded from (link valid till 22.12.2010):

https://www.yousendit.com/download/dklwWWVucHZ6NE5FQlE9PQ

Details


Information

Aims, contents and method of the course

The following topics will be covered:
* sources of X-rays
* crystallisation techniques
* symmetry (point groups, space groups), unit cell, Bravais lattice
* scattering of X-rays, atomic form factor, structure factor
* waves, diffraction of molecules and crystals, Fourier transform; electron density
* set-up of MX diffraction experiment and detectors
* methods for solution of phase problem: molecular replacement, multiple isomorphous replacement, multi-wavelength anomalous dispersion
* density modification techniques
* structure refinement and analysis

Assessment and permitted materials

Oral exam.

Minimum requirements and assessment criteria

Examination topics

Reading list


Association in the course directory

MMB II-2, M205

Last modified: We 19.08.2020 08:08