301123 VO Gene expression (2018S)
Labels
Details
Language: English
Examination dates
- Friday 06.07.2018 15:00 - 20:00 Audimax Zentrum für Translationswissenschaft, Gymnasiumstraße 50
- Friday 05.10.2018
- Friday 30.11.2018 15:00 - 20:00 Audimax Zentrum für Translationswissenschaft, Gymnasiumstraße 50
- Saturday 01.12.2018
- Friday 01.02.2019 15:00 - 20:00 Audimax Zentrum für Translationswissenschaft, Gymnasiumstraße 50
- Friday 12.04.2019
Lecturers
Classes
Ort: IMBA-HS, Dr.Bohrgasse 3, 1030 Wien.
Beginn 6.3.2018
jeweils Di. 9.30 - 11.30 Uhr
Zusätzliche Termine: 17.5. 12.00 - 14.00,18.5. 14.00-16.00 Uhr sowie 30.5. 12.00 - 14.00 Uhr
ACHTUNG, am 19.6.2018 im SR 1/6.Stock, Dr.Bohrgasse 9,1030 Wien.
Information
Aims, contents and method of the course
Assessment and permitted materials
Written exam
Minimum requirements and assessment criteria
Insight and knowledge concerning fundamental principles and mechanisms of transciptional and posstranscriptional regulation of gene expression
points:
10,6 - 12 : very good (1)
9,1-10,5 : good (2)
7,6-9: satisfactory (3)
6-7,5: sufficient (4)
<6: insufficient (5)
points:
10,6 - 12 : very good (1)
9,1-10,5 : good (2)
7,6-9: satisfactory (3)
6-7,5: sufficient (4)
<6: insufficient (5)
Examination topics
Content of the course
Reading list
Slides of the lecture will be provided in Moodle, additional literature or books will be mentioned during the lecture and on the slides
Association in the course directory
BMB 2, BMG 4, B-BMB 2, B-BMG 4, BAN 6,BBO 8, BOE 11,BPB 11,BZO 11
Last modified: Mo 07.09.2020 15:44
1. Molecular mechanisms of transcriptional control in bacteria - promoters and their recognition by RNA polymerase - Mechanisms of transcriptional control of bacterial operons: activators, repressors, 2-component systems
2. Molecular mechanisms of transcriptional control in eukaryotes: - Promotors of RNA Polymerases I, II and III - methodology for the analysis of gene expression - structure-function relationships in transcription factors - Transcriptional initiation general transcription factors and coactivators - chromatin structure and its influence on transcriptional activity of RNA polymerase II - signals and molecular mechanisms of transcription factor activation
3. RNA processing - RNA splicing - RNA stability in bacteria and eukaryots
4. Translation and translational control in in bacteria and eukaryots - Regulation and function of initiation factors - Translational elongation and reprogramming of the genetic code - Translational termination and ribosome recycling