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301123 VO Gene expression (2020S)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie

Registration/Deregistration

Details

Language: English

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

see german version

Tuesday 10.03. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Friday 13.03. 14:30 - 16:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 17.03. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 24.03. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 31.03. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 21.04. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 28.04. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 05.05. 09:30 - 11:30 STB/Hörsaal A Campus Vienna Biocenter 5, 1030 Wien
Tuesday 12.05. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 19.05. 09:30 - 11:30 STB/Hörsaal A Campus Vienna Biocenter 5, 1030 Wien
Tuesday 26.05. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 09.06. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 16.06. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 23.06. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3
Tuesday 30.06. 09:30 - 11:30 Hörsaal IMBA 1030 Wien, Dr.-Bohr-Gasse 3

Information

Aims, contents and method of the course

Lecture Content:
1. Molecular mechanisms of transcriptional control in bacteria - promoters and their recognition by RNA polymerase - Mechanisms of transcriptional control of bacterial operons: activators, repressors, 2-component systems
2. Molecular mechanisms of transcriptional control in eukaryotes: - Promotors of RNA Polymerases I, II and III - methodology for the analysis of gene expression - structure-function relationships in transcription factors - Transcriptional initiation general transcription factors and coactivators - chromatin structure and its influence on transcriptional activity of RNA polymerase II - signals and molecular mechanisms of transcription factor activation
3. RNA processing - RNA splicing - RNA stability in bacteria and eukaryots
4. Translation and translational control in in bacteria and eukaryots - Regulation and function of initiation factors - Translational elongation and reprogramming of the genetic code - Translational termination and ribosome recycling

Assessment and permitted materials

Written exam

Minimum requirements and assessment criteria

Insight and knowledge concerning fundamental principles and mechanisms of transciptional and posstranscriptional regulation of gene expression
points:
10,6 - 12 points: very good (1)
9,1-10,5 points: good (2)
7,6-9 points: satisfactory (3)
6-7,5 points: sufficient (4)
<6 points: insufficient (5)

Examination topics

Content of the course

Reading list

Will be announced in the first lecture hour of the respective lecturer
Decker: Latchman: Gene Control, second ed. Armstrong: Epigentics Lim/Mayer/Pawson: Cell signaling

Association in the course directory

BMB 2, BMG 4

Last modified: We 25.11.2020 08:48