301123 VO Gene expression (2023S)
Labels
Registration/Deregistration
Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
Details
Language: English
Examination dates
- Friday 07.07.2023 15:00 - 20:00 Audimax Zentrum für Translationswissenschaft, Gymnasiumstraße 50
- Friday 06.10.2023 15:00 - 20:00 Audimax Zentrum für Translationswissenschaft, Gymnasiumstraße 50
- Friday 24.11.2023 15:00 - 20:00 Audimax Zentrum für Translationswissenschaft, Gymnasiumstraße 50
- Friday 26.01.2024 15:00 - 20:00 Audimax Zentrum für Translationswissenschaft, Gymnasiumstraße 50
Lecturers
Classes (iCal) - next class is marked with N
see german version
- Tuesday 07.03. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Wednesday 15.03. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 21.03. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 28.03. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 18.04. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 25.04. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 02.05. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 09.05. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 16.05. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 23.05. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 06.06. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 13.06. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 20.06. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Tuesday 27.06. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
- Friday 30.06. 15:00 - 16:30 Hörsaal 1, Biologie Djerassiplatz 1, 0.037, Ebene 0
Information
Aims, contents and method of the course
Assessment and permitted materials
Written exam
Minimum requirements and assessment criteria
Written exam about fundamental principles and mechanisms of transcriptional and post-transcriptional regulation of gene expression.
Mode: Two questions will be asked about both transcription control and post-transcriptional control of gene expression. One of the four questions may be asked in multiple choice mode (not in case of online exams) the remaining answers should be given in the form of short essays, sketches, keywords etc. Each question will be scored with a maximum of 3 points and converted into grades according to the following scheme:10,6 - 12 points: very good (1)
9,1-10,5 points: good (2)
7,6-9 points: satisfactory (3)
6-7,5 points: sufficient (4)
<6 points: insufficient (5)
Mode: Two questions will be asked about both transcription control and post-transcriptional control of gene expression. One of the four questions may be asked in multiple choice mode (not in case of online exams) the remaining answers should be given in the form of short essays, sketches, keywords etc. Each question will be scored with a maximum of 3 points and converted into grades according to the following scheme:10,6 - 12 points: very good (1)
9,1-10,5 points: good (2)
7,6-9 points: satisfactory (3)
6-7,5 points: sufficient (4)
<6 points: insufficient (5)
Examination topics
Content of the course
Reading list
Will be announced in the first lecture hour of the respective lecturer
Decker: Latchman: Gene Control, second ed. Armstrong: Epigentics Lim/Mayer/Pawson: Cell signaling
Decker: Latchman: Gene Control, second ed. Armstrong: Epigentics Lim/Mayer/Pawson: Cell signaling
Association in the course directory
BMB 2, BMG 4
Last modified: Mo 22.01.2024 12:46
1. Molecular mechanisms of transcriptional control in bacteria - promoters and their recognition by RNA polymerase - Mechanisms of transcriptional control of bacterial operons: activators, repressors, 2-component systems
2. Molecular mechanisms of transcriptional control in eukaryotes: - Promotors of RNA Polymerases I, II and III - methodology for the analysis of gene expression - structure-function relationships in transcription factors - Transcriptional initiation general transcription factors and coactivators - chromatin structure and its influence on transcriptional activity of RNA polymerase II - signals and molecular mechanisms of transcription factor activation
3. RNA processing - RNA splicing - RNA stability in bacteria and eukaryots
4. Translation and translational control in in bacteria and eukaryots - Regulation and function of initiation factors - Translational elongation and reprogramming of the genetic code - Translational termination and ribosome recycling