Universität Wien
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301123 VO Gene expression (2025S)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie
Tu 04.03. 11:30-13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0

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Details

Language: English

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

see german version

  • Tuesday 11.03. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 18.03. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 25.03. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 01.04. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 08.04. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 29.04. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 06.05. 13:15 - 14:45 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 13.05. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 20.05. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 27.05. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 03.06. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 10.06. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 17.06. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0
  • Tuesday 24.06. 11:30 - 13:00 Hörsaal 2, Biologie Djerassiplatz 1, 0.033, Ebene 0

Information

Aims, contents and method of the course

Lecture Content:
1. Molecular mechanisms of transcriptional control in bacteria - promoters and their recognition by RNA polymerase - Mechanisms of transcriptional control of bacterial operons: activators, repressors, 2-component systems
2. Molecular mechanisms of transcriptional control in eukaryotes: - Promotors of RNA Polymerases I, II and III - methodology for the analysis of gene expression - structure-function relationships in transcription factors - Transcriptional initiation general transcription factors and coactivators - chromatin structure and its influence on transcriptional activity of RNA polymerase II - signals and molecular mechanisms of transcription factor activation
3. RNA processing - RNA splicing - RNA stability in bacteria and eukaryots
4. Translation and translational control in in bacteria and eukaryots - Regulation and function of initiation factors - Translational elongation and reprogramming of the genetic code - Translational termination and ribosome recycling

Assessment and permitted materials

Written exam

Minimum requirements and assessment criteria

Written exam about fundamental principles and mechanisms of transcriptional and post-transcriptional regulation of gene expression.
Mode: Two questions will be asked about both transcription control and post-transcriptional control of gene expression. One of the four questions may be asked in multiple choice mode (not in case of online exams) the remaining answers should be given in the form of short essays, sketches, keywords etc. Each question will be scored with a maximum of 3 points and converted into grades according to the following scheme:

10,6 - 12 points: very good (1)
9,1-10,5 points: good (2)
7,6-9 points: satisfactory (3)
6-7,5 points: sufficient (4)
<6 points: insufficient (5)

Examination topics

Content of the course

Reading list

Will be announced in the first lecture hour of the respective lecturer
Decker: Latchman: Gene Control, second ed. Armstrong: Epigentics Lim/Mayer/Pawson: Cell signaling

Association in the course directory

BMB 2, BMG 4

Last modified: Fr 10.01.2025 00:02