Universität Wien
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301180 UE Advanced genetics: C.elegans (2025S)

10.00 ECTS (6.00 SWS), SPL 30 - Biologie
Continuous assessment of course work

Details

max. 12 participants
Language: English

Lecturers

    Classes

    see german version


    Information

    Aims, contents and method of the course

    2 week advanced course for the genetic model system C. elegans, covering classical forward and reverse genetics, as well as more recent methods of targeted genome editing. Topics:
    - Introduction to C. elegans as an experimental model
    - Classical forward genetics incl. genetic mapping and epistasis
    - Reverse genetics (RNAi)
    - Targeted genome manipulation by homologous recombination
    - Cellular analysis by immunofluorescence microscopy
    - Seminars on current C. elegans research at the Vienna Biocenter campus
    Priority will be given to those students who have successfully completed the lecture series 301652 VO Advanced topics in Chromosome and RNA Biology (WS)

    Assessment and permitted materials

    Grading is based on class participation including carrying out course experiments and written protocol (~20 pages). There will be no final exam. Instead students are each responsible for one of the course experiments.

    Minimum requirements and assessment criteria

    Attendance mandatory (taking time off during the course only possible with the prior agreement of the instructors and if compatible with ongoing experiments). Grading is as follows: Class participation: 16 (40%) points; written protocol: 16 points (40%); supervision of course experiment: 8 points (20%). Each part must be completed successfully for a passing grade.
    Grading scheme:
    36-40 points: very good (1)
    31-35 points: good (2)
    26-30 points: satisfactory (3)
    20-25 points: sufficient (4)
    <19 points: insufficient (5)

    Examination topics

    There will be no final exam. Instead students will be responsible in pairs for one of the course experiments. Key here is the successful orientation of the class for the day’s experiments, the collection of results and their interpretation. Written protocols should include a brief introduction to each experiment, a description of methods and results as well as a discussion of results obtained (if any). Evaluation of course participation includes active participation in class discussion and carrying out experiments.

    Reading list

    Course manual. This will be distributed several weeks before the course. Individual topics will be covered in detail on the blackboard during the course.

    Association in the course directory

    MMB III-3a:,

    Last modified: Fr 10.01.2025 00:02