301450 VO Macromolecular Crystallography (2019S)
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Registration/Deregistration
Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
Details
Language: English
Examination dates
Lecturers
Classes
Lectures of Macromolecular crystallography will be according to this schedule:
Date Day Time09.04.19 TUE 16-1910.04.19 WED 15-18
11.04.19 THU 16-19
12.04.19 FR 16-19
EASTER HOLIDAYS29.04.19 MO 15-18
30.04.19 TUE 16-1902.05.19 THU 16-19
03.05.19 FR 16-1907.05.19 TUE 16-19
08.05.19 WED 15-18
09.05.19 THU 16-19
10.05.19 FR 16-1914.05.19 TUE 16-19
15.05.19 WED 15-18
16.05.19 THU 16-19
17.05.19 FR 16-19
In the Seminar room of Dept. Structural and Computational Biology, Campus Vienna Biocenter /5, 1030 Wien.
Information
Aims, contents and method of the course
The following topics will be covered the major topic of macromolecular crystallography and will provide students with a comprehensive overview of all the steps required to generate a three-dimensional structural information on biological macromolecules:* sources of X-rays* crystallisation techniques* symmetry (point groups, space groups), unit cell, Bravais lattice* scattering of X-rays, atomic form factor, structure factor* waves, diffraction of molecules and crystals, Fourier transform; electron density* set-up of MX diffraction experiment and detectors* methods for solution of phase problem: molecular replacement, multiple isomorphous replacement, multi-wavelength anomalous dispersion* density modification techniques* structure refinement, structure validation and analysis
Assessment and permitted materials
Oral or written exam, depending on the number of students.
Minimum requirements and assessment criteria
Examination topics
Reading list
Association in the course directory
MMB II-2, MMB W-2, MMEI III, CHE II-6
Last modified: We 19.08.2020 08:08