Universität Wien

301618 VO+SE Structural Biology II (2022S)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie
REMOTE
Moodle

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Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
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Details

Language: English

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

Every Thursday 10.00 - 12.00 Uhr Via Zoom
http://www.univie.ac.at/biolchem/location.html
Lecture notes are available on Moodle.

  • Thursday 03.03. 10:00 - 12:00 Digital
  • Thursday 10.03. 10:00 - 12:00 Digital
  • Thursday 17.03. 10:00 - 12:00 Digital
  • Thursday 24.03. 10:00 - 12:00 Digital
  • Thursday 31.03. 10:00 - 12:00 Digital
  • Thursday 07.04. 10:00 - 12:00 Digital
  • Thursday 28.04. 10:00 - 12:00 Digital
  • Thursday 05.05. 10:00 - 12:00 Digital
  • Thursday 12.05. 10:00 - 12:00 Digital
  • Thursday 19.05. 10:00 - 12:00 Digital
  • Thursday 02.06. 10:00 - 12:00 Digital
  • Thursday 09.06. 10:00 - 12:00 Digital
  • Thursday 23.06. 10:00 - 12:00 Digital
  • Thursday 30.06. 10:00 - 12:00 Digital

Information

Aims, contents and method of the course

Thermodynamics - introduction
Thermodynamics - experimental determination of binding affinities with examples
Thermodynamics - protein folding/unfolding, differential scanning calorimetry
Analysis and validation of macromolecular 3D structures
Protein dynamics at different scales
Structural basis of allosteric regulation
Conformational selection versus induced fit
Periodic table of Protein complexes
The dark proteome intrinsically disordered proteins
Structural basis of affinity and specificity with examples
Reaction mechanisms as reaction kinetics

Assessment and permitted materials

Minimum requirements and assessment criteria

Minimum requirements and assessment criteria
Attendance and active participation during the lecture course, >60% correct answers of exam for passing grade.
Assessment criteria:
100-90%: excellent (1)
89-80%: good (2)
79-70%: satisfactory (3)
69-60%: sufficient (4)
< 59%: insufficient (5)

Examination topics

Contents of the lectures as given in the course lecture notes and handouts available on the Moodle.

Reading list

A list of possible textbooks will be presented in the first lecture. Additional references are given throughout the lectures.

Association in the course directory

BMB 9

Last modified: Th 11.05.2023 11:28