Universität Wien

301618 VO+SE Structural Biology II (2024S)

3.00 ECTS (2.00 SWS), SPL 30 - Biologie
Moodle

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Details

Language: English

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

  • Thursday 07.03. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 14.03. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 21.03. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 11.04. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 18.04. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 25.04. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 02.05. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 16.05. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 23.05. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 06.06. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 13.06. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien
  • Thursday 20.06. 10:00 - 12:00 BZB/Seminarraum 1/2, 6.Ebene 6.501/6.504, Dr.-Bohr-Gasse 9, 1030 Wien

Information

Aims, contents and method of the course

Thermodynamics - introduction
Thermodynamics - experimental determination of binding affinities with examples
Thermodynamics - protein folding/unfolding, differential scanning calorimetry
Analysis and validation of macromolecular 3D structures
Protein dynamics at different scales
Structural basis of allosteric regulation
Conformational selection versus induced fit
Periodic table of Protein complexes
The dark proteome intrinsically disordered proteins
Structural basis of affinity and specificity with examples
Reaction mechanisms as reaction kinetics

Assessment and permitted materials

Minimum requirements and assessment criteria

Minimum requirements and assessment criteria
Attendance and active participation during the lecture course, >60% correct answers of exam for passing grade.
Assessment criteria:
100-90%: excellent (1)
89-80%: good (2)
79-70%: satisfactory (3)
69-60%: sufficient (4)
< 59%: insufficient (5)

Examination topics

Contents of the lectures as given in the course lecture notes and handouts available on the Moodle.

Reading list

A list of possible textbooks will be presented in the first lecture. Additional references are given throughout the lectures.

Association in the course directory

BMB 9

Last modified: Mo 24.02.2025 13:27