Universität Wien FIND

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301853 UE Practical Course in Structural Biology A (2019W)


5.00 ECTS (4.00 SWS), SPL 30 - Biologie
Continuous assessment of course work



max. 20 participants
Language: English



Place: Department of Structural and Computational Biology, Campus-Vienna-Biocenter 5, 1030 Vienna, room 1113

Time: 14 - 28 October 2019, all day long

Start: 14 October 2019, 10:00 am

No pre-meeting: interested students come directly to the beginning of the practical

Knowledge in structural biology, NMR spectroscopy, X-ray crystallography. Previous attendance at the course Macromolecular Crystallography (301450 VO) is strongly recommended.
For external students: Admission requirements for these exercises are courses with continous assessment (UE) that are required for admission to the study.


Aims, contents and method of the course

The course consists of three parts:
1. Application of optical methods to protein stability (chemical and thermal denaturation followed by absorption, fluoresence, circular dichroism and calorimetry).
2. Applications of NMR spectroscopy to relevant problems of molecular biology. The basic principles of the methodology are explained and demonstrated with practical applications to structural biology.
3. Macromolecular Crystallography. Basic principles of crystallisation and structure solution.

Assessment and permitted materials

Compulsory attendance; the evaluation consists of different performances: active participation and results obtained, written report, theoretical knowledge including final exam (the percentage of the subgrades will be announced by the course leader); each of the subgrades must have a positive evaluation.

Minimum requirements and assessment criteria

Theoretical knowledge in basics of structural biology, spectroscopy, and diffraction theory, as well as active participation in conducting experiments and their careful evaluation.

Examination topics

Reading list

Association in the course directory

MMB II-3, MMB II-4, MMB W-2, MMB W-3, M-WZB, CHE II-6, PhD MB 1

Last modified: Mo 14.10.2019 09:08