Universität Wien FIND

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301853 UE Practical Course in Structural Biology A (2020S)

Basics

5.00 ECTS (4.00 SWS), SPL 30 - Biologie
Continuous assessment of course work

Registration/Deregistration

Details

max. 16 participants
Language: German, English

Lecturers

Classes

Place: Department of Structural and Computational Biology, Campus-Vienna-Biocenter 5, 1030 Vienna, room 1113

Time: 16- 30 March 2020, all day long

Start: 16 March 2020, 9:00 am

No pre-meeting: interested students come directly to the beginning of the practical

Requirements:
Knowledge in structural biology, NMR spectroscopy, X-ray crystallography. Previous attendance at the course Macromolecular Crystallography (301450 VO) is strongly recommended.

For external students: Admission requirements for these exercises are courses with continuous assessment (UE) that are required for admission to the study.


Information

Aims, contents and method of the course

The course consists of three parts:
1. Application of optical methods to protein stability (chemical and thermal denaturation followed by absorption, fluoresence, circular dichroism and calorimetry).
2. Applications of NMR spectroscopy to relevant problems of molecular biology. The basic principles of the methodology are explained and demonstrated with practical applications to structural biology.
3. Macromolecular Crystallography. Basic principles of crystallisation and structure solution.

Assessment and permitted materials

The evaluation consists of different performances: active participation and results obtained, written report, theoretical knowledge including final exam.

Minimum requirements and assessment criteria

Compulsory attendance.
Theoretical knowledge in basics of structural biology, spectroscopy, and diffraction theory, as well as active participation in conducting experiments and their careful evaluation.
Each of the subgrades must have a positive evaluation.

Examination topics

Content of the course units

Reading list


Association in the course directory

MMB II-3, MMB II-4, MMB W-2, MMB W-3, MMEI III, CHE II-6

Last modified: We 04.03.2020 17:09