Universität Wien FIND

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301853 UE Practical Course in Structural Biology A (2020W)


5.00 ECTS (4.00 SWS), SPL 30 - Biologie
Continuous assessment of course work


Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).


max. 20 participants
Language: English



Ort: Department für Strukturbiologie und Computational Biology, Campus-Vienna-Biocenter 5, 1030 Wien, Raum 1.116

Zeit: 19. - 30.10.2020, ganztägig

Beginn: 19.10.2020, 09.00 Uhr

Keine Vorbesprechung: interessierte Studierenden kommen direkt zum Beginn der praktischen Arbeiten. Alle Studierenden müssen sich am Eingang der Max Perutz Labs (im Hauptgebäude) anmelden.

Vorkenntnisse aus Strukturbiologie, NMR-Spektroskopie, Röntgenkristallographie. Die vorherige Teilnahme an der Lehrveranstaltung Makromolekulare Kristallographie (301450 VO)
wird wärmstens empfohlen.

Für externe Studierende: Zulassungsvoraussetzungen für diese Übungen sind prüfungsimmanente Lehrveranstaltungen (UE) der Auflagen zur Studienzulassung.


Aims, contents and method of the course

The course consists of three parts:
1. Application of optical methods to protein stability (chemical and thermal denaturation followed by absorption, fluoresence, circular dichroism and calorimetry).
2. Applications of NMR spectroscopy to relevant problems of molecular biology. The basic principles of the methodology are explained and demonstrated with practical applications to structural biology.
3. Macromolecular Crystallography. Basic principles of crystallisation and structure solution.

Assessment and permitted materials

The evaluation consists of different performances: active participation and results obtained, written report, theoretical knowledge including final exam.

Minimum requirements and assessment criteria

Compulsory attendance.
Theoretical knowledge in basics of structural biology, spectroscopy, and diffraction theory, as well as active participation in conducting experiments and their careful evaluation.
Each of the subgrades must have a positive evaluation.

Examination topics

Content of the course units

Reading list

Association in the course directory

MMB II-3, MMB II-4, MMB W-2, MMB W-3, M-WZB, CHE II-6, PhD MB 1

Last modified: We 21.04.2021 11:27