320029 VO General principles of drug action and pharmakokinetics (2013S)
Labels
Beginn: 12.03.2013
Di, Mi 12.30-14.00 Uhr HS 7
ACHTUNG! am 10.04./17.04.und 23.04.2013 findet die VO im Hs 6 statt!!Prüfungstermine:
25.04.2013 10.30 Uhr HS 8
20.06.2013 10.00 Uhr Hs 7
09.08.2013 wird noch bekannt gegeben!
20.09.2013 wird noch bekannt gegeben!
Di, Mi 12.30-14.00 Uhr HS 7
ACHTUNG! am 10.04./17.04.und 23.04.2013 findet die VO im Hs 6 statt!!Prüfungstermine:
25.04.2013 10.30 Uhr HS 8
20.06.2013 10.00 Uhr Hs 7
09.08.2013 wird noch bekannt gegeben!
20.09.2013 wird noch bekannt gegeben!
Details
Language: German
Examination dates
Thursday
20.06.2013
Thursday
25.07.2013
Friday
09.08.2013
Friday
16.08.2013
Friday
20.09.2013
Thursday
05.12.2013
12:00 - 14:00
UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
Thursday
23.01.2014
12:00 - 14:00
UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
Thursday
20.02.2014
10:00 - 12:00
UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
Thursday
08.05.2014
13:00 - 15:00
UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
Lecturers
Classes
Currently no class schedule is known.
Information
Aims, contents and method of the course
Drug-receptor-interactions, classification of different targets for drug action (receptors, ion channels, enzymes, carrier molecules), structure and functions of selected receptors (ligand-gated ion channels, G-protein-coupled receptors, nuclear receptors, kinase-linked receptors), pharmacology of second messenger systems (e.g. the adenylate cyclase/cyclic AMP system and the phospholipase C/inositol phosphate system), interaction of ion channels with G-proteins, the molecular architecture of voltage gated ion channels, their function and pharmacological properties, the release of chemical mediators, routes of drug administration, absorption, distribution, elimination (phase I reactions, the cytochrome P450 system), phase II reactions, first pass effect, active drug metabolites, renal excretion, pharmacokinetics (including compartment models), the autonomic nervous system (cholinergic and noradrenergic transmission, transmission by purines and 5-hydroxytryptamin), peptides and proteins as drugs, nitric oxide, local hormones.
Assessment and permitted materials
Minimum requirements and assessment criteria
To describe the general principles of drug action with focus on cellular and molecular mechanisms and signal transduction cascades. The course includes the mechanisms of drug absorption, distribution and elimination and pharmacokinetics.
Examination topics
Reading list
Association in the course directory
A225
Last modified: Sa 02.04.2022 00:27