320043 VO Cell Biology Principles (2009W)
Cell Biology Principles essential for Pharmacology
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05.10.2009 Vorbesprechung um 13:15 auf 2D265
Beginn: 11.01.2010, 17:00 h
Beginn: 11.01.2010, 17:00 h
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This is an introductory course in principles of cell biology essential in pharmacology. A series of lectures and small group sessions designed to illustrate the principles of cellular functions and methods used in cell biology and to introduce students to the use, advantages, and pitfalls of transgenic animal models in pharmacological research. The course integrates interactive learning focused on the mechanisms of drug action taught in the "Pharmacology and Toxicology" course.The small group sessions offer an extended interaction with faculty member on a topic selected by the student.
Examination topics
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A400
Last modified: Fr 31.08.2018 08:57
o Intracellular transport mechanisms
o Endocytosis
o Cytoskeleton, cell-cell communication
o Basal membrane and extracellular matrix" Signal transduction
o Chemical properties and requirements of the ligand
o Receptor properties for binding of agonist and antagonists
o Intracellular second messanger systems
o Role of kinases and phosphatases" Methods
o Cell culture, biochemistry- immunoprecipitation, Immunohistochemistry
o Design and application of transgenic animals as defined animal models
o Investigation of intracellular proteins and ions (confocal laser scanning microscopy, ratiometric fluorescence quantification of intracellular ion concentrations)