320150 VO Clinical pharmacy and chemical Diagnostics (2007S)

ECTS: 2.5
Intruduction to Clinical Pharmacy: definition and aims
Fundamentals of individual drug therapy
Introduction of main factors that influence drug levels in patients (nutrition, gender, age metabolism, polymorphismus, pharmacogenetics, protein binding, pKa-values)
Patientselective calculation of dose (therapeutic drug monitoring: examples with selected drugs)
Discussion of clinical pharmacy related data listed in the Austria Codex (examples)
Pharmacoepidemiology and pharmacooeconomics
fundamentals of chemical diagnostics
sample preparation and analytics from biological matrix
biostatistics
Importance, description and methods of quantification of laboratory parameters: electrolytes, trace elements, metabolic products, substrates, enzymes, proteins, lipids, hormones.
Selected chapters: oxidative stress, tumour markers,