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320152 PR Drug analysis and drug development (2011W)
Continuous assessment of course work
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Die oben genannten Termine beziehen sich nur auf Seminartermine innerhalb des Praktikums! VOR-Anmeldung für das Praktikum über das Web unter: http://www.univie.ac.at/ulg-pqm/anmeldung-aawe. Zusätzlich ist die persönliche Anmeldung notwendig, da die Erfüllung der Zulassungsvoraussetzungen geprüft werden muss:
Montag, 03.10.2011, 12.00, im Seminarraum 2F248
Dienstag, 04.10.2011, 12.00, im Seminarraum 2F248
Bitte den Ausdruck der elektronischen Anmeldung sowie ein aktuelles Sammelzeugnis mitbringen!
Beginn des Praktikums: Fr, 07.10.2011, 12.00 Uhr (Einführungsbesprechung HS 8)
Montag, 03.10.2011, 12.00, im Seminarraum 2F248
Dienstag, 04.10.2011, 12.00, im Seminarraum 2F248
Bitte den Ausdruck der elektronischen Anmeldung sowie ein aktuelles Sammelzeugnis mitbringen!
Beginn des Praktikums: Fr, 07.10.2011, 12.00 Uhr (Einführungsbesprechung HS 8)
Details
Language: German
Lecturers
- Ernst Urban
- Andrea Deutsch
- Mehrdad Dirin
- Gerhard Ecker
- Christiane Gebhard
- Andreas Jurik
- Freya Klepsch
- Martin Kratzel
- Bodo Lachmann
- Petra Memminger
- Sebastien Queva
- Michael Sonntagbauer
- Martina Stessl
- Elisabeth Strizsik
- Petra Urach
- Johannes Winkler
Classes (iCal) - next class is marked with N
- Friday 07.10. 12:00 - 15:00 UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
- Monday 10.10. 12:00 - 13:00 UZA2 Hörsaal 5 (Raum 2Z202) 2.OG
- Monday 17.10. 12:00 - 13:00 UZA2 Hörsaal 5 (Raum 2Z202) 2.OG
- Monday 24.10. 12:00 - 13:00 UZA2 Hörsaal 5 (Raum 2Z202) 2.OG
- Thursday 03.11. 12:00 - 14:00 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
- Thursday 17.11. 12:00 - 13:00 UZA2 Hörsaal 5 (Raum 2Z202) 2.OG
- Thursday 24.11. 12:00 - 13:00 UZA2 Hörsaal 5 (Raum 2Z202) 2.OG
Information
Aims, contents and method of the course
Assessment and permitted materials
Minimum requirements and assessment criteria
Teaching aim:Main objective: Knowledge how to guarantee the pharmaceutical quality of drugs and how to identify and optimize drugs. Experience in handling the instruments used in quantitative analysis and syntheses; knowledge on computer assisted drug design; development of the ability for method selection, practical running, evaluation and documentation of analytical results.
Examination topics
Reading list
Association in the course directory
A303
Last modified: Sa 02.04.2022 00:27
A: Quantitative determination of active substances in drugs (single compounds, mixtures, impurities) with instrumental methods:
Methods: Spectrophotometry, conductometry, potentiometry, amperometry, polarography, polarimetry, ion selective measurement, water content according to Karl-Fischer, HPLC with refraction index, UV, and fluorescent detection, capillary electrophoresis, enzymatic methods.
Studies concerning the pharmaceutical quality of active ingedients: identity, content, purity, impurity profile; determination of a drug with three selected methods (teamwork), validation of the analytical methods, statistical evaluation, GLP analysis, and discussion of methods and results.
B. Analytical, in silico and special synthetic methods in drug design (lead structure finding and lead structure optimization):
Genome und proteome analysis; biophysical pharmaceutical chemistry (microcalorimetry, ORCD measurements), in vitro and in silico interaction studies, molecular modeling, analysis of structure activity relationships, special synthetic methods (libaries by parallel or combinatorial solid phase synthesis, peptide synthesis, and oligonucleotide synthesis), documentation (chemical part of a "drug master file" - general, synthesis, analysis).