Universität Wien

321010 VO Principles of Drug Synthesis - B6 (2021S)

7.00 ECTS (4.00 SWS), SPL 32 - Pharmazie

Vorlesungszeiten:
01.03. - 30.04.2021 Mo-Fr. 09.45-11.15 Uhr HS 8
Keine VO am 12.04.2021!!

Moodle

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Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).
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Details

Language: German

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

ACHTUNG: Auf Grund der aktuellen Corona-Situation wird diese Lehrveranstaltung ausschließlich online angeboten. Die einzelnen Termine werden gespeichert und sind jederzeit abrufbar.

  • Monday 01.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 02.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 03.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 04.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 05.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 08.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 09.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 10.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 11.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 15.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 16.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 17.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 18.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 19.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 22.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 23.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 24.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 25.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 26.03. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 13.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 14.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 15.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 16.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 19.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 20.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 21.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 22.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 23.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Monday 26.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Tuesday 27.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Wednesday 28.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Thursday 29.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG
  • Friday 30.04. 09:45 - 11:15 Hybride Lehre
    UZA2 Hörsaal 8 (Raum 2Z206) 2.OG

Information

Aims, contents and method of the course

The objective of the course is to teach the student the basic principles of organic chemistry focuse on drug syntheses.
Atomic orbitals; covalent bondings, stereochemistry, chirality; saturated and unsaturated carbohydrates, alkyl halides, alcohols, phenols, ether, sulfur containing compounds, aldehydes, ketones, carboxylic acids and derivatives, carbonic acid and derivatives; M- and I-effects, organic acids and bases; nucleophilic substitution: SN1, SN2,SNi; rearrangement reactions of carbonium ions, hydride shift, allylic rearrangement, Wagner-Meerwein- and Pincol-rearrangement, Hoffmann-Schmidt-rearrangement, Baeyer-Villiger-reactin; elektrophilic and nucleophilic substitution reactions on aromatic compounds, reaktions of diazonium-compounds; additions on C=C-double bonds; Diels-Alder-reactions; addition reactions on C=O-groups: acetals as protecting groups, imines, enamines reductive amination, hydride- and Grignard-reactions; aldol- and Knoevenagel-reactions, Perkin- and benzoin condensation and benzilic acid rearrangement, Wittig- and Mannich-reaction; haloform-reaction, reactions of carboxylic acid derivatives, esterification – hydrolysis of carboxylic esters, Claisen- and Dieckmann-condensation, cleavage of b-Ketoestern; eliminations, Hoffmann-elimination; reactions of radicals: anti-Markownikoff-orientation, allylic halogenation, Kolbe-synthesis, acyloin-condensation, radical reactions on alkenes, Sandmayer-reaction; syntheses of heterocyclic compounds: fundamental principles, quinolines, cumarines, furanes, thiophenes, pyrroles, hydantoines, indoles, pyridines, dihydropyridines; functional group interconversion.

Assessment and permitted materials

Written Examination
Duration: 120 Min.

Minimum requirements and assessment criteria

Marks:
1 = 37-40 P 2 = 33-36 P 3 = 29-32 P 4 = 24-28 P 5 = < 24 P

Examination topics

Lecture

Reading list

"Wie funktionieren organische Reaktionen", P. Sykes, Verlag Chemie
"Reaktionsmechanismen der Organischen Chemie" P. Sykes, Verlag Chemie
"Lehrbuch der organischen Chemie", H. Beyer, S. Hirzel Verlag Stuttgart
"Chemie II", E. Ehlers, Deutscher Apothekerverlag
"Das Basiswissen der organischen Chemie", J. Bülle, A. Hüttermann, Thieme-Verlag
"Organische Chemie", H. Hart, L. E. Craine, D. J. Hart, C. M. Hadad, Wiley-VCH
"Organikum", Heinz Becker (Ed.), Wiley-VCH

Association in the course directory

A105, BA10

Last modified: Fr 12.05.2023 00:24