Universität Wien

321020 VO Introduction to General Pharmacology and Pharmacokinetics - B11 (2020S)

4.00 ECTS (2.00 SWS), SPL 32 - Pharmazie

Infos unter: https://pharmtox.univie.ac.at/studenten/vorlesungsverzeichnis/vorlesungsverzeichnis-sommersemester/
Moodle

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Details

Language: German

Examination dates

Lecturers

Classes (iCal) - next class is marked with N

Due to the current situation this course is offered as e-learning and home-learning course. More information can be found on the Moodle platform!

  • Tuesday 03.03. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Wednesday 04.03. 16:45 - 18:15 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
  • Thursday 05.03. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Tuesday 10.03. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Wednesday 11.03. 16:45 - 18:15 UZA2 Hörsaal 6 (Raum 2Z227) 2.OG
  • Tuesday 17.03. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Thursday 19.03. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Tuesday 24.03. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Thursday 26.03. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Tuesday 31.03. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Thursday 02.04. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Tuesday 21.04. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Thursday 23.04. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Tuesday 28.04. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Thursday 30.04. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Tuesday 05.05. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG
  • Thursday 07.05. 16:45 - 18:15 UZA2 Hörsaal 7 (Raum 2Z210) 2.OG

Information

Aims, contents and method of the course

Teaching aim: Presentation of the general principles of drug effects. The focus is on cellular and molecular mechanisms and relevant signal transduction cascades. The lecture discusses absorption, distribution, excretion and pharmacokinetics of drugs.
Contents: Pharmacon-receptor interactions, classification of different receptor types (membrane receptors, ion channels, enzymes, carrier molecules), structure and function of selected receptors (ligand-activated ion channels, 7-helix receptors, nuclear receptors, receptor protein kinases), pharmacological influence on important "second messenger" systems (e.g. adenylate cyclase/cAMP system, phospholipase C/inositol phosphate system), interaction of ion channels with G proteins, molecular architecture, function and pharmacology of voltage-dependent ion channels, pharmacological influence on the contraction of skeletal muscle and heart muscle cells, mechanisms of release of mediators, modes of drug application, absorption, Distribution, elimination (phase I reactions, the cytochrome P450 system), phase II reactions, first pass effect, active metabolites, renal excretion, pharmacokinetics (including various compartment models), the autonomic nervous system (cholinergic, noradrenergic, purinergic and serotonergic transmission), peptides and proteins as drugs, nitric oxide, local hormones.

Assessment and permitted materials

Written examination
The type of questions is free (open questions, assignments, MC questions, calculations, etc.)
Weighting of the questions (e.g. 1-5 points)
Examination time: 120 minutes

Minimum requirements and assessment criteria

28 - 26 points: grade 1
25 - 22 points: grade 2
21 - 19 points: grade 3
18 - 15 points: grade 4
14 - 0 points: grade 5

In order to pass the examination at least 7.5 points for Part 1/Hering and at least 7.5 points for Part 2/Hoffmann have to be achieved.

Presence examination! This examination will take place at the university.

Examination topics

Lecture notes

Reading list

Allgemeine und spezielle Pharmakologie und Toxikologie
Aktories, Förstermann, Hofmann, Starke; 11. Auflage
Arzneimittelwirkungen, Ernst Mutschler, Herausgeber; neueste Auflage
Pharmakokinetik kompakt, Derendorf, Gramatte, Schäfer, Staab; 3.Auflage

Association in the course directory

A225, BA20

Last modified: Sa 02.04.2022 00:27