322050 VU Special strategies for the structure elucidation of drugs and natural products by NMR - M14 (2023W)
Continuous assessment of course work
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Language: German
Lecturers
Classes
Die VU findet an folgenden Terminen immer donnerstags im Seminarraum Pharmakognosie 2D404 statt (UZA2 Ebene 4 Spange D).
5. Oktober: 9.15-11.15 Uhr
12. Oktober: 9.15-11.15 Uhr
19. Oktober: 9.15-11.15 Uhr
9. November: 10.15-11.15 Uhr
16. November: 10.15-11.15 Uhr
30. November: 9.15-11.15 Uhr
07. Dezember: 10.15-11.15 Uhr
Information
Aims, contents and method of the course
Assessment and permitted materials
Course with continuous assessment (VU) with compulsory attendance.
The performance control takes place through active participation in class and through homework examples.
The performance control takes place through active participation in class and through homework examples.
Minimum requirements and assessment criteria
For the positive assessment, all homework examples must be solved.
Examination topics
Content taught in the lecture
Reading list
Independent studying of literature is not necessary. For those interested: further literature listed in the Moodle course
Association in the course directory
MA23
Last modified: We 23.08.2023 10:28
• Introduction to software tools for the processing of NMR spectra (e.g. Bruker TopSpin)
• Discussion of successful structure elucidation examples of pharmaceutically relevant compounds and isolated compounds from natural sources
• Structure elucidation examples of the following structure classes: flavonoids, alkaloids, triterpenes, sesquiterpenes, aromatics and heteroaromatics, nucleosides, antibiotics, peptides, ...
• Stereochemistry: Which NMR experiments are useful and helpful for the determination of stereochemistry? Interpretation based on examples
• Discussion of problems and cases of doubt in structure elucidation with NMRAim: Independent structural elucidation of simple small molecules by evaluating and interpreting 1D and 2D NMR spectra
Optionally participants can bring their own examples