Universität Wien

322050 VU Special strategies for the structure elucidation of drugs and natural products by NMR - M14 (2024S)

1.00 ECTS (1.00 SWS), SPL 32 - Pharmazie
Continuous assessment of course work

Vorlesungszeiten:
Moodle

Registration/Deregistration

Note: The time of your registration within the registration period has no effect on the allocation of places (no first come, first served).

Details

Language: German

Lecturers

Classes

Die VU findet an folgenden Terminen immer donnerstags im Seminarraum Pharmakognosie 2D404 statt (UZA2 Ebene 4 Spange D).
7. März: 9.15-11.15 Uhr
14. März: 9.15-11.15 Uhr
21. März: 9.15-11.15 Uhr
11. April: 9.15-11.15 Uhr
18. April: 10.15-11.15 Uhr
25. April: 10.15-11.15 Uhr
2. Mai: 10.15-11.15 Uhr

Information

Aims, contents and method of the course

• Introduction to 1D and 2D NMR techniques commonly used today to determine the structure of drugs and compounds from natural sources (small molecules)
• Introduction to software tools for the processing of NMR spectra (e.g. Bruker TopSpin)
• Discussion of successful structure elucidation examples of pharmaceutically relevant compounds and isolated compounds from natural sources
• Structure elucidation examples of the following structure classes: flavonoids, alkaloids, triterpenes, sesquiterpenes, aromatics and heteroaromatics, nucleosides, antibiotics, peptides, ...
• Stereochemistry: Which NMR experiments are useful and helpful for the determination of stereochemistry? Interpretation based on examples
• Discussion of problems and cases of doubt in structure elucidation with NMR

Aim: Independent structural elucidation of simple small molecules by evaluating and interpreting 1D and 2D NMR spectra
Optionally participants can bring their own examples

Assessment and permitted materials

Course with continuous assessment (VU) with compulsory attendance.
The performance control takes place through active participation in class and through homework examples.

Minimum requirements and assessment criteria

For the positive assessment, all homework examples must be solved.

Examination topics

Content taught in the lecture

Reading list

Independent studying of literature is not necessary. For those interested: further literature listed in the Moodle course

Association in the course directory

MA23

Last modified: Th 06.06.2024 13:06