Universität Wien FIND

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322077 VU Overcoming the Skin Barrier: Drug Delivery via the Dermal Route - M7 (2020W)

1.00 ECTS (1.00 SWS), SPL 32 - Pharmazie
Continuous assessment of course work

Details

Language: German

Lecturers

Classes

Die Termine für WS2020/21 finden im Januar 2021 statt.
Uhrzeit: jeweils 10:30 bis 12:00. Ort: Seminarraum 2D404.

Die Anzahl an TeilnehmerInnen ist begrenzt, daher bitte um rechtzeitige Anmeldung im Sekretariat Pharmazeutische Technologie und Biopharmazie (sonja.holzmann@univie.ac.at). Platzvergabe erfolgt nach Zeitpunkt der Anmeldung.

14.1.2021
15.1.2021
20.1.2021
22.1.2021
25.1.2021
27.1.2021
29.1.2021

Anmerkung: Sollte die Präsenzlehre aufgrund der aktuellen Covid19 - Situation eingeschränkt sein, findet die Lehrveranstaltung digital via Moodle-Kurs statt.


Information

Aims, contents and method of the course

The aim of this course is to obtain an overview about the development of dermal formulations and the techniques required for their production and characterisation. Contents include skin biology, colloidal formulations in the nanometer range, high and low energy production techniques as well as established methods for characterisation of dermal formulations and skin itself (formulation analysis: optical light microscopy and electron microscopy, light scattering techniques, rheology; skin analysis: TEWL, hydration, pH, sebum; penetration/permeation analysis: diffusion cells, tape stripping, ATR-FTIR spectroscopy, confocal Raman spectroscopy).

Methods: The contents are presented and discussed by means of ppt presentations.

Assessment and permitted materials

Short written examinations are handed out every two sessions.

Minimum requirements and assessment criteria

At least 2 out of 3 tests have to be passed (positive assessment). The grade reflects the average performance at these three assignments.

Examination topics

Contents of the presentations.

Reading list

Literatur zum Thema Haut und Penetration von Arzneistoffen:
- Percutaneous Penetration Enhancers, Eds. Dragicevic & Maibach, Springer (2015)
- Transdermal Drug Delivery, Eds. Guy & Hadgraft, Marcel Dekker Inc, 2nd edition (2002)
- Mechanisms of Transdermal Drug Delivery, Ed. Potts, CRC Press, 1st edition (1997)

Literatur zum Thema kolloidale Arzneiformen:
- Bauer/Frömming/Führer: Pharmazeutische Technologie (Eds. Lippold/Müller-Goymann/Schubert, Wiss. Verlagsges. Stuttgart, 10. Auflage, 2017)
- Innovative Arzneiformen (Eds. Mäder & Weidenauer, Wiss. Verlagsges. Stuttgart, 2009)
- Voigt: Pharmazeutische Technologie für Studium und Beruf (Ed. Fahr, Wiss. Verlagsges. Stuttgart, 12. Auflage, 2015)

Literatur zu den besprochenen Methoden:
- Grundlagen der Licht- und Elektronenmikroskopie, Ed. Linnemann & Kühl, UTB GmbH, 2017.
- Laser Light Scattering, Eds. Johnson & Gabriel, Dover Classics, Dover Publications Inc., 1995.
- Zetapotential und Partikelladung in der Laborpraxis, Ed. Müller, Wiss. Verlagsges. Stuttgart, 1996.
- Spektroskopische Methoden in der organischen Chemie, Eds. Hesse, Meier, Zeeh, Thieme, 2005.
- Confocal Raman Microscopy, Eds. Dieing, Hollricher, Toporski, Springer-Verlag Berlin Heidelberg, 2011.
- Das Rheologie-Handbuch, Ed. Mezger, Vincentz Network, 2016.

Association in the course directory

MA8, MA23, A400

Last modified: Tu 25.08.2020 12:09