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323001 VU Introduction to Drug Discovery and Preclinical Drug Development - MPS1 (2017W)

5.00 ECTS (2.00 SWS), SPL 32 - Pharmazie
Continuous assessment of course work


Language: English



2017-10-02, 14.00h-17:00h: UZA2 2D313
2017-10-03, 14.00h-17:00h: UZA2 2D313
2017-10-04, 14.00h-17:00h: UZA2 2D358
2017-10-05, 14.00h-17:00h: UZA2 2D313
2017-10-10, 14.00h-17:00h: UZA2 2D313
2017-10-11, 14.00h-17:00h: UZA2 2D358
2017-10-12, 14.00h-17:00h: UZA2 2D313
2017-10-13, 14.00h-17:00h: UZA2 2D411
2017-10-17, 14.00h-17:00h: UZA2 2D313
2017-10-18, 14.00h-17:00h: UZA2 2D358
2017-10-19, 14.00h-17:00h: UZA2 2D313
2017-10-22, 14.00h-17:00h: UZA2 2D313


Aims, contents and method of the course

The students will be introduced to basic principles in drug discovery. The course will consist of presentations given by the faculty, as well as presentations given by students, followed by round table discussions.

Assessment and permitted materials

There will be one written exam at the end of the course.
The grades will be deduced to 40% from the result in the written exam, to 30% from the quality of the oral presentations and 30 % from the active participation in the discussions during the course.

Minimum requirements and assessment criteria

The student should possess basic knowledge in principles of drug discovery. Topics will cover target identification and validation, structural biology, hit identification and validation, lead structure identification and optimization and hereby be able to understand and comprehensively and critically present original papers / projects /ideas to these topics.

Examination topics

All topics covered during the course.

Reading list

Some useful literature can be found in the following publications:
- Benjamin E. Blass: Basic Principles of Drug Discovery and Development (Academic Press, ISBN 978-0-12-411508-8)
- Raymond Hill: Drug Discovery and Development: Technology in Transition (Churchill Livingstone Elsevier, ISBN 976-0-7020-4299-7)
- Jeffrey Strovel et al.: Early Drug Discovery and Development Guidelines: For Academic Researchers, Collaborators, and Start-up Companies (https://www.ncbi.nlm.nih.gov/books/NBK92015/pdf/Bookshelf_NBK92015.pdf)

Association in the course directory

Last modified: Fr 31.08.2018 08:43